Evidence map›Paper›PMID 29089403›Full record

Trial reportPediatrics2017

Cost-Effectiveness of a Clinical Childhood Obesity Intervention.

Mona Sharifi, Calvin Franz, Christine M Horan, Catherine M Giles, Michael W Long, Zachary J Ward, Stephen C Resch, Richard Marshall, Steven L Gortmaker, Elsie M Taveras

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04196556 (Effectiveness of an Intervention Programme), which is not on this map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04196556 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Effectiveness of an Intervention Programme (FAMILIAS ACTIVAS) for Childhood Obesity: Cluster Randomized Controlled Trial

TypeinterventionalSponsorGerencia de Atención Primaria, MadridRan2022 to 2024Enrolled253ConditionsChildhood ObesityArmsActive Families, Madrid's Primary Healthcare Standardized Service portfolio
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  5. Water First School Water Promotion and Access Intervention: A Cost Analysis Study.Journal of the Academy of Nutrition and Dietetics · 2025
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  7. Cost-Effectiveness and Long-Term Savings of the Bright Bodies Intervention for Childhood Obesity.Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mona SharifiDepartment of Pediatrics, Section of General Pediatrics, Yale University School of Medicine, New Haven, Connecticut; mona.sharifi@yale.edu.
Calvin FranzEastern Research Group Inc, Lexington, Massachusetts.
Christine M HoranDivision of General Academic Pediatrics, Department of Pediatrics, Massachusetts General Hospital for Children, Boston, Massachusetts.
Catherine M GilesDepartments of Social and Behavioral Sciences and.
Michael W LongDepartment of Prevention and Community Health, Milken Institute School of Public Health, George Washington University, Washington, District of Columbia; and.
Zachary J WardDepartments of Social and Behavioral Sciences and.
Stephen C ReschCenter for Health Decision Science, Harvard T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts.
Richard MarshallDepartment of Pediatrics, Harvard Vanguard Medical Associates and Atrius Health Inc, Boston, Massachusetts.
Steven L GortmakerDepartments of Social and Behavioral Sciences and.
Elsie M TaverasDivision of General Academic Pediatrics, Department of Pediatrics, Massachusetts General Hospital for Children, Boston, Massachusetts.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
HARVARD PREVENTION RESEARCH CENTER ON NUTRITION AND PHYSICAL ACTIVITY-CATEGORY 1U48DP001946 · DP · HARVARD SCHOOL OF PUBLIC HEALTH · PI GORTMAKER, STEVEN L · 2009 to 2013
$7.5M
Mentored Career Development for Child and Family Centered Outcomes ResearchK12HS022986 · AHRQ · BOSTON CHILDREN'S HOSPITAL · PI FINKELSTEIN, JONATHAN A · 2014 to 2018
$3.8M
Patient Oriented Research and Mentorship in Childhood Obesity DisparitiesK24DK105989 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI TAVERAS BENAVIDEZ, ELSIE MIREYA · 2015 to 2019
$907k
Using Electronic Health Records to Support Decision-Making in Pediatric Obesity CareK08HS024332 · AHRQ · YALE UNIVERSITY · PI SHARIFI, MAHNOOSH · 2016 to 2018
$461k
AHRQ HHS K08 HS024332AHRQ HHS K12 HS022986NCATS NIH HHS UL1 TR001863NCCDPHP CDC HHS U48 DP001946NIDDK NIH HHS K24 DK105989
6 · The paper itself

Abstract

objectivesTo estimate the cost-effectiveness and population impact of the national implementation of the Study of Technology to Accelerate Research (STAR) intervention for childhood obesity.

methodsIn the STAR cluster-randomized trial, 6- to 12-year-old children with obesity seen at pediatric practices with electronic health record (EHR)-based decision support for primary care providers and self-guided behavior-change support for parents had significantly smaller increases in BMI than children who received usual care. We used a microsimulation model of a national implementation of STAR from 2015 to 2025 among all pediatric primary care providers in the United States with fully functional EHRs to estimate cost, impact on obesity prevalence, and cost-effectiveness.

resultsThe expected population reach of a 10-year national implementation is ∼2 million children, with intervention costs of $119 per child and $237 per BMI unit reduced. At 10 years, assuming maintenance of effect, the intervention is expected to avert 43 000 cases and 226 000 life-years with obesity at a net cost of $4085 per case and $774 per life-year with obesity averted. Limiting implementation to large practices and using higher estimates of EHR adoption improved both cost-effectiveness and reach, whereas decreasing the maintenance of the intervention's effect worsened the former.

conclusionsA childhood obesity intervention with electronic decision support for clinicians and self-guided behavior-change support for parents may be more cost-effective than previous clinical interventions. Effective and efficient interventions that target children with obesity are necessary and could work in synergy with population-level prevention strategies to accelerate progress in reducing obesity prevalence.

Indexed as

Body Mass IndexCost-Benefit AnalysisDecision Making, Computer-AssistedChildEarly Medical InterventionElectronic Health RecordsFemaleHumansMalePediatric ObesityUnited States

Identifiers

PMID29089403
PMCPMC5654390

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.