Evidence map›Paper›PMID 29089360›Full record

ReviewDevelopment (Cambridge, England)2017

Cortical interneuron development: a tale of time and space.

Jia Sheng Hu, Daniel Vogt, Magnus Sandberg, John L Rubenstein

Abstract readReview
In one paragraph

Review in Development (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 123 papers.

0numbers the graph read from it
0cells of the map it votes in
123citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

123 citing papers in PubMed.

  1. Article
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  17. Review
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  20. Article

63 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jia Sheng HuDepartment of Psychiatry, University of California, San Francisco, CA 94158, USA.ORCID 0000-0002-2530-2051
Daniel VogtDepartment of Psychiatry, University of California, San Francisco, CA 94158, USA.ORCID 0000-0003-1876-5936
Magnus SandbergDepartment of Psychiatry, University of California, San Francisco, CA 94158, USA.ORCID 0000-0003-0809-0656
John L RubensteinDepartment of Psychiatry, University of California, San Francisco, CA 94158, USA john.rubenstein@ucsf.edu.ORCID 0000-0002-4414-7667

Funding

Genetic Control of Basal Telencephalic DevelopmentR01MH081880 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RUBENSTEIN, JOHN L. R. · 2009 to 2023
$8.1M
Genetic Regulation of Telencephalon DevelopmentR37MH049428 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RUBENSTEIN, JOHN L. R. · 2008 to 2017
$5.9M
STRUCTURE, EXPRESSION &FUNCTION OF THE DLX GENE FAMILYR01MH049428 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RUBENSTEIN, JOHN L. R. · 1992 to 2022
$5.8M
Neurobiological Mechanisms Underlying the Symptoms and Course of SchizophreniaT32MH089920 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FORD, JUDITH M · 2010 to 2014
$1.3M
NIMH NIH HHS R01 MH049428NIMH NIH HHS R01 MH081880NIMH NIH HHS R37 MH049428NIMH NIH HHS T32 MH089920
6 · The paper itself

Abstract

Cortical interneurons are a diverse group of neurons that project locally and are crucial for regulating information processing and flow throughout the cortex. Recent studies in mice have advanced our understanding of how these neurons are specified, migrate and mature. Here, we evaluate new findings that provide insights into the development of cortical interneurons and that shed light on when their fate is determined, on the influence that regional domains have on their development, and on the role that key transcription factors and other crucial regulatory genes play in these events. We focus on cortical interneurons that are derived from the medial ganglionic eminence, as most studies have examined this interneuron population. We also assess how these data inform our understanding of neuropsychiatric disease and discuss the potential role of cortical interneurons in cell-based therapies.

Indexed as

AnimalsCell LineageCerebral CortexInterneuronsModels, BiologicalTime FactorsTranscription, GeneticCell fateCortical interneuronsMGEParvalbuminSomatostatinTranscription factors

Identifiers

PMID29089360
PMCPMC5702067

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.