ArticleBMJ (Clinical research ed.)2017
Circulating vitamin D concentration and risk of seven cancers: Mendelian randomisation study.
Registry-linked trialOpen access · bronzeAbstract read
In one paragraph
Article in BMJ (Clinical research ed.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02328677 (ColoCare Transdisciplinary Research in Colorectal Cancer Prognosis), which is not on this map. Cited by 98 papers, 12 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed, 12 pooled it
14.3field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
ColoCare Transdisciplinary Research in Colorectal Cancer Prognosis
Who cites it
98 citing papers in PubMed, 12 syntheses or guidelines pooled it, 171 citations in OpenAlex.
- Risk factors of ovarian cancer: a systematic review and meta-analysis of Mendelian randomiation studies.Journal of public health (Oxford, England) · 2026Pooled it
- Vitamin D and Pancreatic Ductal Adenocarcinoma-A Review of a Complicated Relationship.Nutrients · 2024Pooled it
- Pooled it
- Vitamin D and human health: evidence from Mendelian randomization studies.European journal of epidemiology · 2024Pooled it
- Serum 25-Hydroxyvitamin D and Cancer Risk: A Systematic Review of Mendelian Randomization Studies.Nutrients · 2023Pooled it
- Association between psoriasis and lung cancer: two-sample Mendelian randomization analyses.BMC pulmonary medicine · 2023Pooled it
- Vitamin D and Multiple Health Outcomes: An Umbrella Review of Observational Studies, Randomized Controlled Trials, and Mendelian Randomization Studies.Advances in nutrition (Bethesda, Md.) · 2022Pooled it
- Systematic review of Mendelian randomization studies on risk of cancer.BMC medicine · 2022Pooled it
- Pooled it
- 25-Hydroxyvitamin D status, vitamin D intake, and skin cancer risk: a systematic review and dose-response meta-analysis of prospective studies.Scientific reports · 2020Pooled it
- Vitamin D supplementation and total cancer incidence and mortality: a meta-analysis of randomized controlled trials.Annals of oncology : official journal of the European Society for Medical Oncology · 2019Pooled it
- Vitamin D and breast cancer: A systematic review and meta-analysis of observational studies.Clinical nutrition ESPEN · 2019Pooled it
- Active monitoring, radical prostatectomy and radical radiotherapy in PSA-detected clinically localised prostate cancer: the ProtecT three-arm RCT.Health technology assessment (Winchester, England) · 2020Trial
- Monthly High-Dose Vitamin D Supplementation and Cancer Risk: A Post Hoc Analysis of the Vitamin D Assessment Randomized Clinical Trial.JAMA oncology · 2018Trial
- Exploring causality in the association between circulating 25-hydroxyvitamin D and colorectal cancer risk: a large Mendelian randomisation study.BMC medicine · 2018Trial
- Early Versus Late Initiation of Renal Replacement Therapy Impacts Early Mortality in Diabetic Patients with Acute Kidney Injury After Cardiac Surgery.Journal of cardiovascular development and disease · 2026Article
- The Dual Role of the Gut Microbiota in Cancer Chemoresistance.MicrobiologyOpen · 2026Review
- Causal relationships between gut microbiota, C-reactive protein levels and colorectal cancer: A Mendelian randomization study.Medicine · 2026Article
- Vitamin D and Health Outcomes: State-of-the-Art Review of Triangulated Evidence and Ongoing Controversies.Current nutrition reports · 2026Review
- Vitamin D deficiency and long-term risk of female genital cancer: a multicenter real-world cohort study.Frontiers in nutrition · 2026Article
38 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
24 authors at 16 institutions in 6 countries.
Vasiliki I DimitrakopoulouDepartment of Hygiene and Epidemiology, School of Medicine, University of Ioannina, Ioannina, Greece.
Konstantinos K TsilidisDepartment of Hygiene and Epidemiology, School of Medicine, University of Ioannina, Ioannina, Greece ktsilidi@cc.uoi.gr.
Philip C HaycockSchool of Social and Community Medicine, University of Bristol, Bristol, UK.
Niki L DimouDepartment of Hygiene and Epidemiology, School of Medicine, University of Ioannina, Ioannina, Greece.
Kawthar Al-DabhaniDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
Richard M MartinSchool of Social and Community Medicine, University of Bristol, Bristol, UK.
Sarah J LewisSchool of Social and Community Medicine, University of Bristol, Bristol, UK.
Marc J GunterInternational Agency for Research on Cancer, Lyon, France.
Alison MondulDepartment of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA.
Irene M ShuiDepartment of Epidemiology, Harvard School of Public Health, Boston, MA, USA.
Evropi TheodoratouCentre of Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburg, Edinburgh, UK.
Katharina NimptschMolecular Epidemiology Research Group, Max Delbrück Centre for Molecular Medicine (MDC), Berlin, Germany.
Sara LindströmDepartment of Epidemiology, University of Washington, Seattle, WA, USA.
Demetrius AlbanesDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
Tilman KühnDivision of Cancer Epidemiology, German Cancer Research Centre (DKFZ), Heidelberg, Germany.
Timothy J KeyCancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Ruth C TravisCancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Karani Santhanakrishnan VimaleswaranDepartment of Food and Nutritional Sciences, Hugh Sinclair Unit of Human Nutrition and Institute for Cardiovascular and Metabolic Research (ICMR), University of Reading, Reading, UK.
GECCO Consortium
PRACTICAL Consortium
GAME-ON Network (CORECT, DRIVE, ELLIPSE, FOCI-OCAC, TRICL-ILCCO)
Peter KraftProgram in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA.
Brandon L PierceDepartment of Public Health Sciences, University of Chicago, Chicago, IL, USA.
Joellen M SchildkrautDepartment of Public Health Sciences, University of Virginia, Charlottesville, VA, USA.
Chicago Department of Public Health · USUniversity of Bristol · GBUniversity of Ioannina · GRUniversity of Oxford · GBCentre international de recherche sur le cancer · FRGerman Cancer Research Center · DEHarvard University · USImperial College London · GBMax Delbrück Center · DENational Cancer Institute · USUniversity College Dublin · IEUniversity Hospitals Bristol NHS Foundation Trust · GBUniversity of Michigan · USUniversity of Reading · GBUniversity of Virginia · USUniversity of Washington · US
Funding
Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) StudyZIACP010195 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI ALBANES, DEMETRIUS · 2009 to 2025
$22.5MDetection of Colorectal Cancer Susceptibility Loci Using Genome-Wide SequencingU01CA164930 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI PETERS, ULRIKE · 2012 to 2015
$12.4MColon Cancer Family Registry CohortUM1CA167551 · NCI · STANFORD UNIVERSITY · PI HAILE, ROBERT WILLIAM, JENKINS, MARK A · 2013 to 2017
$11.3MRisk Prediction of Symptomatic Gallbladder DiseaseK01DK110267 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI JOSHI, AMIT DOLAR · 2016 to 2021
$876kCancer Research UK 14136Cancer Research UK 16491Cancer Research UK 19170Cancer Research UK 22804Medical Research Council G0401527Medical Research Council G1000143Medical Research Council MR/N003284/1NCI NIH HHS U01 CA164930NCI NIH HHS UM1 CA167551NIDDK NIH HHS K01 DK110267World Health Organization 001
Abstract
PubMed holds no abstract for this paper.
Indexed as
Breast NeoplasmsCase-Control StudiesColorectal NeoplasmsFemaleGenetic Predisposition to DiseaseGenetic VariationGenome-Wide Association StudyHumansIncidenceLung NeoplasmsMaleMendelian Randomization AnalysisNeoplasmsNeuroblastomaOvarian NeoplasmsPancreatic Neoplasms25-hydroxyvitamin DVitamin D
Identifiers
What OpenQuestion holds
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LicenceCC BY
Read underepoch 390
Registered trials
NCT02328677ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.