Evidence map›Paper›PMID 29088836›Full record

ArticleOncotarget2017

Common, germline genetic variations in the novel tumor suppressor

Moubin Lin, Liren Zhang, Michelle A T Hildebrandt, Maosheng Huang, Xifeng Wu, Yuanqing Ye

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Advances in urinary biomarker discovery in urological research.Investigative and clinical urology · 2020
    Review
  5. Article
  6. Review
  7. A Subset of Mesotheliomas With Improved Survival Occurring in Carriers of BAP1 and Other Germline Mutations.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2018
    Article
  8. Genetics of metastasis: melanoma and other cancers.Clinical & experimental metastasis · 2018
    Review
  9. Article
  10. Progress in the Management of Malignant Pleural Mesothelioma in 2017.Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Moubin LinDepartment of General Surgery, Yangpu Hospital, Tongji University School of Medicine, Shanghai, People's Republic of China.
Liren ZhangDepartment of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Michelle A T HildebrandtDepartment of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Maosheng HuangDepartment of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Xifeng WuDepartment of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Yuanqing YeDepartment of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
The University of Texas MD Anderson Cancer Center · USYangpu Hospital of Tongji University · CN

Funding

UNIVERSITY OF TEXAS--SPORE IN LUNG CANCERP50CA070907 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI HEYMACH, JOHN V., MINNA, JOHN D. · 1996 to 2024
$57.4M
Targeting Ral GTPases in Bladder CancerP50CA091846 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI DINNEY, COLIN P.N., MCCONKEY, DAVID J. · 2001 to 2018
$37.4M
Genome-Wide Association Analysis of Bladder CancerU01CA127615 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI WU, XIFENG · 2008 to 2012
$5.1M
Markers of Genetic Susceptibility to Bladder CancerR01CA074880 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI WU, XIFENG · 1999 to 2008
$3.1M
Genetic Instability & Risk for Esophageal CarcinomaR01CA111922 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI WU, XIFENG · 2008 to 2012
$2.9M
Epigenetic miRNA, SNP Signatures, and their Functions in Lung Cancer OutcomesR01CA176568 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI GU, JIAN, ROTH, JACK · 2014 to 2018
$2.5M
Molecular pathways linking obesity and RCC tumorigenesis (PQ1)R01CA170298 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI GU, JIAN · 2012 to 2015
$2.1M
NCI NIH HHS P50 CA070907NCI NIH HHS P50 CA091846NCI NIH HHS R01 CA074880NCI NIH HHS R01 CA111922NCI NIH HHS R01 CA170298NCI NIH HHS R01 CA176568NCI NIH HHS U01 CA127615
6 · The paper itself

Abstract

BRCA1 associated protein-1 (BAP1) is a novel tumor suppressor that has recently been shown to be somatically mutated in several cancers. The

Indexed as

BAP1cancer riskSNP

Identifiers

PMID29088836
PMCPMC5650391
OpenAlexW2748988024

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.