Evidence map›Paper›PMID 29088810›Full record

ArticleOncotarget2017

Genetic variants of PDGF signaling pathway genes predict cutaneous melanoma survival.

Hong Li, Yanru Wang, Hongliang Liu, Qiong Shi, Hongyu Li, Wenting Wu, Dakai Zhu, Christopher I Amos, Shenying Fang, Jeffrey E Lee and 3 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. A Functional Synonymous Variant inJournal of Cancer · 2020
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 2 countries.

Hong LiDepartment of Clinical Laboratory, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei 050011, China.
Yanru WangDuke Cancer Institute, Duke Cancer Institute, Duke University Medical Center, Durham, NC 27710, USA.
Hongliang LiuDuke Cancer Institute, Duke Cancer Institute, Duke University Medical Center, Durham, NC 27710, USA.
Qiong ShiDuke Cancer Institute, Duke Cancer Institute, Duke University Medical Center, Durham, NC 27710, USA.
Hongyu LiDuke Cancer Institute, Duke Cancer Institute, Duke University Medical Center, Durham, NC 27710, USA.
Wenting WuDepartment of Epidemiology, Fairbanks School of Public Health, Indiana University Melvin and Bren Simon Cancer Center, Indiana University, Indianapolis, IN 46202, USA.
Dakai ZhuCommunity and Family Medicine, Geisel School of Medicine, Dartmouth College, Hanover, NH 03755, USA.
Christopher I AmosCommunity and Family Medicine, Geisel School of Medicine, Dartmouth College, Hanover, NH 03755, USA.
Shenying FangDepartment of Surgical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.
Jeffrey E LeeDepartment of Surgical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.
Yi LiDepartment of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.
Jiali HanDepartment of Epidemiology, Fairbanks School of Public Health, Indiana University Melvin and Bren Simon Cancer Center, Indiana University, Indianapolis, IN 46202, USA.
Qingyi WeiDuke Cancer Institute, Duke Cancer Institute, Duke University Medical Center, Durham, NC 27710, USA.
Duke University · USDartmouth College · USDuke Medical Center · USThe University of Texas MD Anderson Cancer Center · USFourth Hospital of Hebei Medical University · CNIndiana University Health · USIndiana University IndianapolisUniversity of Michigan–Ann Arbor · US

Funding

Women's Cancer Research ProgramP30CA014236 · NCI · DUKE UNIVERSITY · PI JOHN N. NORTON · 1985 to 2026
$174.8M
Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Fred W Kolling IV · 1985 to 2026
$91.3M
Statistical MethodsP01CA087969 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI ROSNER, BERNARD A · 2000 to 2019
$77.8M
UT M.D. Anderson Cancer Center SPORE in MelanomaP50CA093459 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI GRIMM, ELIZABETH A · 2004 to 2014
$23.7M
Long Term Multidisciplinary Study of Cancer in Women: The Nurses Health StudyUM1CA186107 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI ELIASSEN, A. HEATHER, STAMPFER, MEIR · 2014 to 2023
$22.3M
Cancer Epidemiology Cohort in Male Health ProfessionalsUM1CA167552 · NCI · HARVARD SCHOOL OF PUBLIC HEALTH · PI WILLETT, WALTER C. · 2012 to 2016
$11.5M
BIOCHEMICAL MARKERS IN THE NURSES'HEALTH STUDY COHORTR01CA049449 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI HANKINSON, SUSAN E · 1989 to 2008
$11.3M
BIOCHEMICAL MARKERS IN THE NURSES HEALTH STUDY COHORTU01CA049449 · NCI · UNIVERSITY OF MASSACHUSETTS AMHERST · PI HANKINSON, SUSAN E · 1995 to 2013
$5.4M
Genetic Predictors for DNA Repair Phenotype in CMMR01CA100264 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI WEI, QINGYI · 2004 to 2008
$1.5M
NCI NIH HHS P01 CA087969NCI NIH HHS P30 CA014236NCI NIH HHS P30 CA023108NCI NIH HHS P50 CA093459NCI NIH HHS R01 CA049449NCI NIH HHS R01 CA100264NCI NIH HHS UM1 CA167552NCI NIH HHS UM1 CA186107
6 · The paper itself

Abstract

To investigate whether genetic variants of platelet-derived growth factor (PDGF) signaling pathway genes are associated with survival of cutaneous melanoma (CM) patients, we assessed associations of single-nucleotide polymorphisms in PDGF pathway with melanoma-specific survival in 858 CM patients of M.D. Anderson Cancer Center (MDACC). Additional data of 409 cases from Harvard University were also included for further analysis. We identified 13 SNPs in four genes (

Indexed as

Cox regressioncutaneous melanomaPDGF signaling pathwaysingle nucleotide polymorphisms

Identifiers

PMID29088810
PMCPMC5650365
OpenAlexW2746522207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.