Evidence map›Paper›PMID 29088326›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2018

Safety Evaluation of Efavirenz in Children: Don't Forget the Central Nervous System.

Lisa Van de Wijer, Grace D Kinabo, Deborah N Mchaile, Quirijn de Mast, Arnt F A Schellekens, André J A M van der Ven

Registry-linked trialOpen access · bronzeAbstract readLetterComment
PubMed Publisher
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03227653 (Neuropsychiatric Adverse Effects of Efavirenz in Children Living With HIV in Kilimanjaro, Tanzania), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03227653 completednot on this map

Neuropsychiatric Adverse Effects of Efavirenz in Children Living With HIV in Kilimanjaro, Tanzania

TypeobservationalSponsorRadboud University Medical CenterRan2017 to 2017Enrolled144ConditionsEfavirenz, Child Behavior, Cognitive Symptom, Medication AdherenceArmsEfavirenz, Nevirapine, Lopinavir-Ritonavir Drug Combination
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Reply to Van de Wijer et al.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Lisa Van de WijerDepartment of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
Grace D KinaboDepartment of Pediatrics, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.
Deborah N MchaileDepartment of Pediatrics, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.
Quirijn de MastDepartment of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
Arnt F A SchellekensDepartment of Psychiatry, Radboud University Medical Center, Nijmegen, The Netherlands.
André J A M van der VenDepartment of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
Radboud University Medical Center · NLKilimanjaro Christian Medical Centre · TZRadboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

NevirapineRitonavirAlkynesBenzoxazinesChildCyclopropanesHIVHumansLopinavirNervous SystemAlkynesBenzoxazinesCyclopropanesefavirenzLopinavirNevirapineRitonavir

Identifiers

PMID29088326
OpenAlexW2766878821

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.