Evidence map›Paper›PMID 29087963›Full record

ArticlePhysics in medicine and biology2017

Accelerating volumetric cine MRI (VC-MRI) using undersampling for real-time 3D target localization/tracking in radiation therapy: a feasibility study.

Wendy Harris, Fang-Fang Yin, Chunhao Wang, You Zhang, Jing Cai, Lei Ren

Abstract read
In one paragraph

Article in Physics in medicine and biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Observational
  2. Review
  3. Article
  4. Article
  5. Article
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  9. Article
  10. Beyond T2 and 3T: New MRI techniques for clinicians.Clinical and translational radiation oncology · 2019
    Review
  11. Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wendy HarrisMedical Physics Graduate Program, Duke University, 2424 Erwin Road Suite 101, Durham, NC 27705, United States of America.
Fang-Fang YinDepartment of Radiation Oncology, Duke University Medical Center, DUMC Box 3295, Durham, NC 27710, United States of America.
Chunhao WangDepartment of Radiation Oncology, Duke University Medical Center, DUMC Box 3295, Durham, NC 27710, United States of America.
You ZhangMedical Physics Graduate Program, Duke University, 2424 Erwin Road Suite 101, Durham, NC 27705, United States of America.
Jing CaiDepartment of Radiation Oncology, Duke University Medical Center, DUMC Box 3295, Durham, NC 27710, United States of America.
Lei RenDepartment of Radiation Oncology, Duke University Medical Center, DUMC Box 3295, Durham, NC 27710, United States of America.

Funding

A Limited-angle Intra-fractional Verification (LIVE) System for SBRT TreatmentsR01CA184173 · NCI · DUKE UNIVERSITY · PI REN, LEI, YIN, FANG-FANG · 2015 to 2018
$1.5M
NCI NIH HHS R01 CA184173
6 · The paper itself

Abstract

purposeTo accelerate volumetric cine MRI (VC-MRI) using undersampled 2D-cine MRI to provide real-time 3D guidance for gating/target tracking in radiotherapy.

methods4D-MRI is acquired during patient simulation. One phase of the prior 4D-MRI is selected as the prior images, designated as MRI

resultsFor XCAT, VPD/COMS were 11.93  ±  2.37%/0.90  ±  0.27 mm and 11.53  ±  1.47%/0.85  ±  0.20 mm among all scenarios with Cartesian sampling (SP  =  10%) and radial sampling (21 spokes, SP  =  5.2%), respectively. When tumor size decreased, higher sampling rate achieved more accurate VC-MRI than lower sampling rate. VC-MRI was robust against noise levels up to SNR  =  20. For patient data, the tumor tracking errors in superior-inferior, anterior-posterior and lateral (LAT) directions were 0.46  ±  0.20 mm, 0.56  ±  0.17 mm and 0.23  ±  0.16 mm, respectively, for Cartesian-based sampling with SP  =  20% and 0.60  ±  0.19 mm, 0.56  ±  0.22 mm and 0.42  ±  0.15 mm, respectively, for radial-based sampling with SP  =  8% (32 spokes).

conclusionsIt is feasible to estimate VC-MRI from a single undersampled on-board 2D cine MRI. Phantom and patient studies showed that the temporal resolution of VC-MRI can potentially be improved by 5-10 times using a 2D cine image acquired with 10-20% k-space sampling.

Indexed as

Phantoms, ImagingFeasibility StudiesHumansImaging, Three-DimensionalLiver NeoplasmsLung NeoplasmsMagnetic Resonance Imaging, CineMotionRetrospective StudiesTumor Burden

Identifiers

PMID29087963
PMCPMC5756137

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.