Evidence map›Paper›PMID 29087479›Full record

ArticleNucleic acids research2018

STCRDab: the structural T-cell receptor database.

Jinwoo Leem, Saulo H P de Oliveira, Konrad Krawczyk, Charlotte M Deane

Abstract read
In one paragraph

Article in Nucleic acids research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 1 synthesis or guideline pooled it.

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21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jinwoo LeemDepartment of Statistics, University of Oxford, 24-29 St Giles, Oxford, OX1 3LB, UK.
Saulo H P de OliveiraDepartment of Statistics, University of Oxford, 24-29 St Giles, Oxford, OX1 3LB, UK.
Konrad KrawczykDepartment of Statistics, University of Oxford, 24-29 St Giles, Oxford, OX1 3LB, UK.
Charlotte M DeaneDepartment of Statistics, University of Oxford, 24-29 St Giles, Oxford, OX1 3LB, UK.

Funding

Medical Research Council EP/L016044/1
6 · The paper itself

Abstract

The Structural T-cell Receptor Database (STCRDab; http://opig.stats.ox.ac.uk/webapps/stcrdab) is an online resource that automatically collects and curates TCR structural data from the Protein Data Bank. For each entry, the database provides annotations, such as the α/β or γ/δ chain pairings, major histocompatibility complex details, and where available, antigen binding affinities. In addition, the orientation between the variable domains and the canonical forms of the complementarity-determining region loops are also provided. Users can select, view, and download individual or bulk sets of structures based on these criteria. Where available, STCRDab also finds antibody structures that are similar to TCRs, helping users explore the relationship between TCRs and antibodies.

Indexed as

Databases, ProteinSoftwareAmino Acid SequenceAntigensBinding SitesComplementarity Determining RegionsHumansInternetMajor Histocompatibility ComplexModels, MolecularMolecular Sequence AnnotationProtein BindingProtein Conformation, alpha-HelicalProtein Conformation, beta-StrandProtein Interaction Domains and MotifsReceptors, Antigen, T-CellAntigensComplementarity Determining RegionsReceptors, Antigen, T-Cell

Identifiers

PMID29087479
PMCPMC5753249

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.