SynthesisThe American journal of gastroenterology2017
Risk of Advanced Adenoma, Colorectal Cancer, and Colorectal Cancer Mortality in People With Low-Risk Adenomas at Baseline Colonoscopy: A Systematic Review and Meta-Analysis.
Synthesis in The American journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
44 citing papers in PubMed, 1 synthesis or guideline pooled it, 127 citations in OpenAlex.
- Recommendations for Follow-Up After Colonoscopy and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer.The American journal of gastroenterology · 2020Guideline
- Efficacy and Tolerability of Two Different Low-Volume Split-Dose Polyethylene Glycol Electrolytes Solution Bowel Preparation for Morning Colonoscopy.Canadian journal of gastroenterology & hepatology · 2022Trial
- Trial
- Taking a pragmatic approach to implement colonoscopy quality at a health system level: Ontario's colonoscopy quality strategy.Journal of the Canadian Association of Gastroenterology · 2026Article
- Clinicopathological Characteristics of Colorectal Neoplasia in Adults Younger than 50 Years: A Real-World Single-Center Study.Journal of clinical medicine · 2026Article
- Risk of metachronous advanced neoplasia was comparable between patients with 1-2 and 3-4 non-advanced adenomas removed during screening colonoscopy.Surgical endoscopy · 2026Article
- Navigating the Terrain of Post-Polypectomy Surveillance: Charting the Complex Landscape of Guidelines and Recurrence Risks.Canadian journal of gastroenterology & hepatology · 2026Review
- Systemic inflammatory biomarkers (NLR, SII, PNI and FPR) combined with CEA for predicting advanced colorectal neoplasms: development and temporal validation of a machine learning model.Frontiers in oncology · 2026Article
- Impact of Retroactive Application of Updated Surveillance Guidelines on Endoscopy Center Capacity at a Large VA Health Care System.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2025Article
- Surveillance of colorectal neoplasia: a review of guidelines, current evidence, and future directions.Colorectal cancer · 2025Article
- Dynamic adenoma detection rate influences the risk of metachronous advanced neoplasia after removal of low-risk findings in screening colonoscopy.Surgical endoscopy · 2025Observational
- Advanced Adenoma and Long-Term Risk of Colorectal Cancer, Cancer-Related Mortality, and Mortality.JAMA network open · 2025Article
- Provider Adherence to the 2020 US Multi-Society Task Force Guidelines for Surveillance After Colonoscopy With Polypectomy.Gastro hep advances · 2025Article
- Development of a National Colorectal Cancer Screening Research Agenda: An Initiative of the Canadian Screening for Colorectal Cancer Research Network (CanSCCRN).Current oncology (Toronto, Ont.) · 2024Article
- The Interplay among Wnt/β-catenin Family Members in Colorectal Adenomas and Surrounding Tissues.Biomedicines · 2024Article
- Gut microbes on the risk of advanced adenomas.BMC microbiology · 2024Article
- Article
- A survey of current practices in post-polypectomy surveillance in Korea.Intestinal research · 2024Article
- Discovery of extracellular vesicle-delivered miR-185-5p in the plasma of patients as an indicator for advanced adenoma and colorectal cancer.Journal of translational medicine · 2023Article
- Clinical outcomes of colonoscopic polypectomy with strategic surveillance colonoscopies in patients with 10 or more polyps.Scientific reports · 2023Observational
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesWe conducted a systematic review and meta-analysis of the risk of advanced adenomas (AAs), colorectal cancer (CRC), and/or CRC-related death among individuals with low-risk adenomas (LRAs).
methodsWe searched PubMed and Embase for studies published between January 2006 and July 2015. Quality and strength of the evidence were rated using the Newcastle-Ottawa Scale (NOS) and the GRADE framework, respectively.
resultsEleven observational studies (n=64,317) were included. A meta-analysis of eight cohort studies (n=10,139, 3 to 10 years' follow-up) showed a small but statistically significant increase in the incidence of AAs in individuals with LRAs compared with those with a normal baseline colonoscopy (RR 1.55 (95% CI 1.24-1.94); P=0.0001; I
conclusionsWe observed a small but significant increase in the risk of AAs in people with LRAs compared with those with a normal baseline colonoscopy, but compared with the general population, people with LRAs have significantly lower risks of CRC and of CRC-related mortality.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.