Evidence map›Paper›PMID 29087319›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Inhibition of curli assembly and

Neha Jain, Jörgen Ådén, Kanna Nagamatsu, Margery L Evans, Xinyi Li, Brennan McMichael, Magdalena I Ivanova, Fredrik Almqvist, Joel N Buxbaum, Matthew R Chapman

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 64 citations in OpenAlex.

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  5. βProceedings of the National Academy of Sciences of the United States of America · 2026
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  19. Anti-Biofilm Molecules Targeting Functional Amyloids.Antibiotics (Basel, Switzerland) · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Neha JainDepartment of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI 48109-1048.
Jörgen ÅdénDepartment of Chemistry, Umeå University, 901 87 Umeå, Sweden.
Kanna NagamatsuDepartment of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI 48109-1048.
Margery L EvansDepartment of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI 48109-1048.
Xinyi LiDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037.
Brennan McMichaelDepartment of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI 48109-1048.
Magdalena I IvanovaDepartment of Neurology, University of Michigan, Ann Arbor, MI 48109-1048.
Fredrik AlmqvistDepartment of Chemistry, Umeå University, 901 87 Umeå, Sweden.
Joel N BuxbaumDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037; jbux@scripps.edu chapmanm@umich.edu.
Matthew R ChapmanDepartment of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI 48109-1048; jbux@scripps.edu chapmanm@umich.edu.
University of Michigan–Ann Arbor · USScripps Research Institute · USUmeå University · SE

Funding

Cellular Biotechnology Training Program (CBTP)T32GM008353 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SCHWENDEMAN, ANNA · 1991 to 2021
$9.3M
Protein and Chemical Modulation of Curli Amyloid BiogenesisR01GM118651 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Matthew Richard Chapman · 2016 to 2026
$3.0M
Cellular Biotechnology Training Program (CBTP) - Years 31-35T32GM145304 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Guizhi Zhu · 2022 to 2026
$2.6M
BIOGENESIS AND INHIBITION OF BIOFILM-ASSOCIATED BACTERIAL AMYLOIDR01AI099099 · NIAID · WASHINGTON UNIVERSITY · PI FRIEDEN, CARL, HULTGREN, SCOTT J. · 2013 to 2017
$1.9M
NIAID NIH HHS R01 AI099099NIGMS NIH HHS R01 GM118651NIGMS NIH HHS T32 GM008353NIGMS NIH HHS T32 GM145304
6 · The paper itself

Abstract

During biofilm formation,

Indexed as

AmyloidAmyloidogenic ProteinsBinding SitesBiofilmsEscherichia coliEscherichia coli ProteinsGene ExpressionHumansKineticsPrealbuminProtein AggregatesProtein BindingProtein Interaction Domains and MotifsProtein MultimerizationAmyloidAmyloidogenic ProteinscsgA protein, E coliEscherichia coli ProteinsPrealbuminProtein AggregatesamyloidsbiofilmsCsgAcurlitransthyretin

Identifiers

PMID29087319
PMCPMC5699053
OpenAlexW2766612491

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.