Evidence map›Paper›PMID 29087314›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Pathogen-mediated selection in free-ranging elk populations infected by chronic wasting disease.

Ryan J Monello, Nathan L Galloway, Jenny G Powers, Sally A Madsen-Bouterse, William H Edwards, Mary E Wood, Katherine I O'Rourke, Margaret A Wild

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 62 citations in OpenAlex.

  1. Article
  2. Article
  3. Identification of the Highly Polymorphic Prion Protein Gene (Animals : an open access journal from MDPI · 2025
    Article
  4. Article
  5. Article
  6. Large animal models for chronic wasting disease.Cell and tissue research · 2023
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. The First Report of Polymorphisms and Genetic Features of theInternational journal of molecular sciences · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Ryan J MonelloBiological Resources Division, National Park Service, Fort Collins, CO 80525; Ryan_Monello@nps.gov.
Nathan L GallowayBiological Resources Division, National Park Service, Fort Collins, CO 80525.
Jenny G PowersBiological Resources Division, National Park Service, Fort Collins, CO 80525.
Sally A Madsen-BouterseDepartment of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99164.ORCID 0000-0001-6790-7166
William H EdwardsWyoming Game and Fish Department, Laramie, WY 82070.
Mary E WoodWyoming Game and Fish Department, Laramie, WY 82070.
Katherine I O'RourkeAgriculture Research Service, Animal Disease Research Unit, United States Department of Agriculture, Pullman, WA 99164.
Margaret A WildBiological Resources Division, National Park Service, Fort Collins, CO 80525.
National Park Service · USWyoming Game and Fish Department · USUnited States Department of Agriculture · USWashington State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pathogens can exert a large influence on the evolution of hosts via selection for alleles or genotypes that moderate pathogen virulence. Inconsistent interactions between parasites and the host genome, such as those resulting from genetic linkages and environmental stochasticity, have largely prevented observation of this process in wildlife species. We examined the prion protein gene (

Indexed as

AllelesDeerPolymorphism, GeneticAnimalsBayes TheoremConserved SequenceFemaleGene FrequencyGenotypePrion ProteinsSelection, GeneticUnited StatesWasting Disease, ChronicPrion ProteinsCervus elaphuschronic wasting diseaseelkpathogen-mediated selectionprion protein

Identifiers

PMID29087314
PMCPMC5699046
OpenAlexW2765226898

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.