Evidence map›Paper›PMID 29087301›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Estimating mobility using sparse data: Application to human genetic variation.

Liisa Loog, Marta Mirazón Lahr, Mirna Kovacevic, Andrea Manica, Anders Eriksson, Mark G Thomas

Abstract readHistorical Article
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Estimating human mobility in Holocene Western Eurasia with large-scale ancient genomic data.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Pooled it
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  6. Peer community journal · 2023
    Article
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  10. A genomic perspective on South American human history.Genetics and molecular biology · 2022
    Article
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  12. Sometimes hidden but always there: the assumptions underlying genetic inference of demographic histories.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Liisa LoogResearch Department of Genetics, Evolution and Environment, University College London, London WC1E 6BT, United Kingdom; LiisaLoog@gmail.com m.thomas@ucl.ac.uk.
Marta Mirazón LahrLeverhulme Centre for Human Evolutionary Studies, Department of Archaeology and Anthropology, University of Cambridge, Cambridge CB2 1QH, United Kingdom.ORCID 0000-0001-5752-5770
Mirna KovacevicResearch Department of Genetics, Evolution and Environment, University College London, London WC1E 6BT, United Kingdom.
Andrea ManicaDepartment of Zoology, University of Cambridge, Cambridge CB2 3EJ, United Kingdom.
Anders ErikssonDepartment of Medical and Molecular Genetics, King's College London, London SE1 9RT, United Kingdom.ORCID 0000-0003-3436-3726
Mark G ThomasResearch Department of Genetics, Evolution and Environment, University College London, London WC1E 6BT, United Kingdom; LiisaLoog@gmail.com m.thomas@ucl.ac.uk.ORCID 0000-0002-2452-981X

Funding

Wellcome TrustWellcome Trust 100719/Z/12/Z
6 · The paper itself

Abstract

Mobility is one of the most important processes shaping spatiotemporal patterns of variation in genetic, morphological, and cultural traits. However, current approaches for inferring past migration episodes in the fields of archaeology and population genetics lack either temporal resolution or formal quantification of the underlying mobility, are poorly suited to spatially and temporally sparsely sampled data, and permit only limited systematic comparison between different time periods or geographic regions. Here we present an estimator of past mobility that addresses these issues by explicitly linking trait differentiation in space and time. We demonstrate the efficacy of this estimator using spatiotemporally explicit simulations and apply it to a large set of ancient genomic data from Western Eurasia. We identify a sequence of changes in human mobility from the Late Pleistocene to the Iron Age. We find that mobility among European Holocene farmers was significantly higher than among European hunter-gatherers both pre- and postdating the Last Glacial Maximum. We also infer that this Holocene rise in mobility occurred in at least three distinct stages: the first centering on the well-known population expansion at the beginning of the Neolithic, and the second and third centering on the beginning of the Bronze Age and the late Iron Age, respectively. These findings suggest a strong link between technological change and human mobility in Holocene Western Eurasia and demonstrate the utility of this framework for exploring changes in mobility through space and time.

Indexed as

Genetics, PopulationHuman MigrationModels, StatisticalArchaeologyDNA, AncientDNA, MitochondrialEuropeHistory, AncientHumansSequence Analysis, DNASpatio-Temporal AnalysisDNA, AncientDNA, Mitochondrialancient DNAcultural variationmobilitymorphological variationtime-series data

Identifiers

PMID29087301
PMCPMC5699029

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.