ArticleChemistry Central journal2017
Synthesis and biological activity of myricetin derivatives containing 1,3,4-thiadiazole scaffold.
Article in Chemistry Central journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Coumarin derivatives containing the 1,3,4 oxadiazole/thiadiazole moiety discovered as potential anti-tobacco mosaic virus agents.Molecular diversity · 2025Article
- Naringenin restricts the colonization and growth of Ralstonia solanacearum in tobacco mutant KCB-1.Plant physiology · 2024Article
- Antiviral activity evaluation and action mechanism of myricetin derivatives containing thioether quinoline moiety.Molecular diversity · 2024Article
- Design, synthesis, antiviral bioactivities and interaction mechanisms of penta-1,4-diene-3-one oxime ether derivatives containing a quinazolin-4(3BMC chemistry · 2019Article
- Biological activity evaluation and action mechanism of chalcone derivatives containing thiophene sulfonate.RSC advances · 2019Article
- Synthesis and antibacterial and antiviral activities of myricetin derivatives containing a 1,2,4-triazole Schiff base.RSC advances · 2019Article
- Novel chalcone derivatives containing a 1,2,4-triazine moiety: design, synthesis, antibacterial and antiviral activities.RSC advances · 2019Article
- Article
- Design, Synthesis, and Biological Activity of Novel Myricetin Derivatives Containing Amide, Thioether, and 1,3,4-Thiadiazole Moieties.Molecules (Basel, Switzerland) · 2018Article
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Authors and funding
8 authors.
Funding
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Abstract
backgroundMyricetin and 1,3,4-thiadiazole derivatives were reported to exhibit favorable antiviral and antibacterial activities. Aiming to discover novel myricetin analogues with potent activities, a series of novel myricetin derivatives containing 1,3,4-thiadiazole moiety were synthesized, and their antibacterial and antiviral activities were evaluated.
resultBioassay results indicated that some target compounds exhibited potential antibacterial and antiviral activities. Among them, compounds 2, 3a, 3b, 3d, 3f, 3i, 3m and 3p exhibited excellent antibacterial activities against Xanthomonas oryzae pv. Oryzae (Xoo), with EC
conclusionsA series of myricetin derivatives containing 1,3,4-thiadiazole scaffold were synthesized, and their antibacterial activities against Xoo and Rs and their antiviral activity against TMV were evaluated. Bioassays indicated that some target compounds exhibited potential antibacterial and antiviral activities. These results indicated this kind of myricetin analogues could be further studied as potential alternative templates in the search for novel antibacterial and antiviral agents.
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