ArticleChemistry Central journal2017
Antiproliferative and apoptotic effects of black turtle bean extracts on human breast cancer cell line through extrinsic and intrinsic pathway.
Article in Chemistry Central journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- How the Intake of Pulses May Impact Metabolic Disorders and Dementia Risk: A Narrative Review.Nutrients · 2025Review
- Chemopreventive Effect of Cooked Chickpea on Colon Carcinogenesis Evolution in AOM/DSS-Induced Balb/c Mice.Plants (Basel, Switzerland) · 2023Article
- Cancer and apoptosis: The apoptotic activity of plant and marine natural products and their potential as targeted cancer therapeutics.Frontiers in pharmacology · 2022Review
- Apoptosis Effects ofGalen medical journal · 2022Article
- Cytotoxicity, in vivo toxicity, and chemical composition of the hexane extract of Plectranthus amboinicus (Lour.) Spreng.Environmental science and pollution research international · 2021Article
- Breast Cancer: A Global Concern, Diagnostic and Therapeutic Perspectives, Mechanistic Targets in Drug Development.Advanced pharmaceutical bulletin · 2021Review
- Celastrol inhibit the proliferation, invasion and migration of human cervical HeLa cancer cells through down-regulation of MMP-2 and MMP-9.Journal of cellular and molecular medicine · 2021Article
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- A newly isolated strain of Halomonas sp. (HA1) exerts anticancer potential via induction of apoptosis and GScientific reports · 2020Article
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- Article
- Cytotoxic and apoptotic inducing activity of Amoora rohituka leaf extracts in human breast cancer cells.Journal of Ayurveda and integrative medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The black turtle bean (BTB) is most widely consumed legume all over the world having anticancer activity. The aim of the study was to analyse the apoptotic effects of BTB extracts on human breast cancer cell lines. Plant extract was prepared by homogenization and centrifugation. The cytotoxic effects of BTB was evaluated by MTT assay and their apoptotic effects were characterized by DNA fragmentation, nuclear staining assay, mitochondrial membrane potential analysis, annexin-V FITC and caspase 3/7 activity assay. The changes in cell cycle and gene expression of cell lines were analysed by flow cytometry and qRT-PCR, respectively. BTB extract showed cytotoxicity with IC
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Registered trials
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