Evidence map›Paper›PMID 29086527›Full record

ArticleObesity (Silver Spring, Md.)2017

Association Between Weight Loss and the Risk of Cancer after Bariatric Surgery.

Daniel P Schauer, Heather Spencer Feigelson, Corinna Koebnick, Bette Caan, Sheila Weinmann, Anthony C Leonard, J David Powers, Panduranga R Yenumula, David E Arterburn

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Obesity (Silver Spring, Md.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 4 pooled it
9.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 4 syntheses or guidelines pooled it, 89 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. THE GROWING EVIDENCE OF THE RELATIONSHIP BETWEEN OBESITY AND CANCER AND THE ROLE OF BARIATRIC SURGERY.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2024
    Review
  14. Long-term cancer outcomes after bariatric surgery.Obesity (Silver Spring, Md.) · 2023
    Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Daniel P SchauerDivision of General Internal Medicine and Center for Clinical Effectiveness, University of Cincinnati, Cincinnati, Ohio, USA.ORCID 0000-0003-3264-8154
Heather Spencer FeigelsonKaiser Permanente Colorado, Denver, Colorado, USA.
Corinna KoebnickKaiser Permanente Southern California, Pasadena, California, USA.
Bette CaanKaiser Permanente Northern California, Oakland, California, USA.
Sheila WeinmannKaiser Permanente Northwest, Portland, Oregon, USA.
Anthony C LeonardDepartment of Family and Community Medicine, University of Cincinnati Medical Center, Cincinnati, Ohio, USA.
J David PowersKaiser Permanente Colorado, Denver, Colorado, USA.
Panduranga R YenumulaKaiser Permanente Northern California, Oakland, California, USA.
David E ArterburnKaiser Permanente Washington Health Research Institute, Seattle, Washington, USA.
Kaiser Permanente · USCincinnati VA Medical Center · USKaiser Permanente Washington Health Research Institute · USUniversity of Cincinnati · US

Funding

Impact of Bariatric Surgery on Cancer Incidence in Severely Obese AdultsR01CA175346 · NCI · UNIVERSITY OF CINCINNATI · PI SCHAUER, DANIEL P · 2014 to 2016
$2.0M
NCI NIH HHS R01 CA175346
6 · The paper itself

Abstract

objectiveThe goal of this study was to determine whether the reduction in cancer risk after bariatric surgery is due to weight loss.

methodsA retrospective matched cohort study of patients undergoing bariatric surgery was conducted using data from a large integrated health insurance and care delivery system with five sites in four states. The study included 18,355 bariatric surgery subjects and 40,524 nonsurgical subjects matched on age, sex, BMI, site, and Elixhauser comorbidity index. Multivariable Cox proportional hazards models examined the relationship between weight loss at 1 year and incident cancer during up to 10 years of follow-up.

resultsThe study identified 1,196 cases of incident cancer. The average 1-year postsurgical weight loss was 27% among patients undergoing bariatric surgery versus 1% in matched nonsurgical patients. Percent weight loss at 1 year was significantly associated with a reduced risk of any cancer in adjusted models (HR 0.897, 95% CI: 0.832-0.968, P = 0.005 for every 10% weight loss) while bariatric surgery was not a significant independent predictor of cancer incidence.

conclusionsWeight loss after bariatric surgery was associated with a lower risk of incident cancer. There was no apparent independent effect of the bariatric surgery itself on cancer risk that was independent of weight loss.

Indexed as

Weight LossAdultBariatric SurgeryCohort StudiesFemaleHumansIncidenceInsurance Claim ReviewMaleMiddle AgedNeoplasmsObesityRetrospective StudiesRiskUnited States

Identifiers

PMID29086527
PMCPMC5722457
OpenAlexW2766984078

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.