ReviewThe British journal of dermatology2017
The pathogenesis of cutaneous squamous cell carcinoma in organ transplant recipients.
Review in The British journal of dermatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 75 citations in OpenAlex.
- Topical treatment of actinic keratoses in organ transplant recipients: a feasibility study for SPOT (Squamous cell carcinoma Prevention in Organ transplant recipients using Topical treatments).The British journal of dermatology · 2022Trial
- Nonmelanoma Skin Cancer in South Florida: A Change in the Relative Incidence of Basal and Squamous Cell Carcinoma.The Journal of clinical and aesthetic dermatology · 2025Article
- Analysis of race in time to keratinocyte carcinoma in solid organ transplant recipients: Results of a single-institution study.Journal of the American Academy of Dermatology · 2025Article
- Human papillomavirus-associated skin cancers among organ transplant recipients: A systematic review and meta-analysis.Caspian journal of internal medicine · 2025Review
- Review
- Current Advances and Challenges in the Management of Cutaneous Squamous Cell Carcinoma in Immunosuppressed Patients.Cancers · 2024Review
- Article
- Frequency of skin diseases in renal transplant recipients and patients with chronic kidney disease in a tertiary center: a cross-sectional study.Sao Paulo medical journal = Revista paulista de medicina · 2024Observational
- Skin and gut microbial associations with squamous cell carcinoma in solid organ transplant recipients.Archives of dermatological research · 2023Article
- Management of Cutaneous Head and Neck Squamous and Basal Cell Carcinomas for Immunocompromised Patients.Cancers · 2023Review
- Identifying risk factors for cutaneous disease among solid organ transplant recipients: A retrospective review.JAAD international · 2023Article
- Pharmacological Agents Used in the Prevention and Treatment of Actinic Keratosis: A Review.International journal of molecular sciences · 2023Review
- Article
- TargetingFrontiers in oncology · 2023Article
- Aggressive Cutaneous Squamous Cell Carcinomas Following Treatment for Graft-versus-Host Disease: A Case Report and Review of Risk Factors.Dermatopathology (Basel, Switzerland) · 2022Article
- NONMELANOMA SKIN CANCER IN A HEART TRANSPLANT PATIENT: A CASE REPORT AND REVIEW OF THE LITERATURE.Acta clinica Croatica · 2022Review
- Update of advanced cutaneous squamous cell carcinoma.Journal of the European Academy of Dermatology and Venereology : JEADV · 2022Review
- Skin conditions in liver transplant recipients in a Singapore academic medical center: A retrospective cohort study.JAAD international · 2021Article
- Involvement of transcribed lncRNA uc.291 and SWI/SNF complex in cutaneous squamous cell carcinoma.Discover oncology · 2021Article
- 5'-Cap‒Dependent Translation as a Potent Therapeutic Target for Lethal Human Squamous Cell Carcinoma.The Journal of investigative dermatology · 2021Article
Corrections and comments
- Commented on by
Authors and funding
8 authors at 7 institutions in 5 countries.
Funding
Abstract
The pathogenesis of keratinocyte carcinoma following organ transplantation is multifactorial, and recent evidence suggests a complex and often synergistic interplay between the carcinogenic effects of ultraviolet radiation, compromised immune surveillance, direct pro- and anticarcinogenic effects of drugs, oncogenic viruses (in particular, beta-genus human papillomaviruses) and host genetic susceptibility factors. We present an overview of those factors for which there is currently the most convincing evidence and highlight important gaps in our knowledge. In particular, a clear understanding of the interdependence and relative contributions of these co-factors is currently lacking, yet has important implications for rational development of clinically relevant biomarkers and targeted strategies for treatment and prevention of post-transplant keratinocyte cancers.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.