Evidence map›Paper›PMID 29086412›Full record

ReviewThe British journal of dermatology2017

Research gaps in the management and prevention of cutaneous squamous cell carcinoma in organ transplant recipients.

M Blomberg, S Y He, C Harwood, S T Arron, S Demehri, A Green, M M Asgari, NCI Keratinocyte Carcinoma Consortium

Open access · greenAbstract readReview
In one paragraph

Review in The British journal of dermatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 61 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Photoprotection according to skin phototype and dermatoses: practical recommendations from an expert panel.Journal of the European Academy of Dermatology and Venereology : JEADV · 2021
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Skin cancer management-updates on Merkel cell carcinoma.Annals of translational medicine · 2018
    Review
  12. Article
  13. Article
  14. Follow-up of liver transplant recipients.Best practice & research. Clinical gastroenterology
    Review
  15. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

M BlombergDepartment of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, U.S.A.
S Y HeDepartment of Dermatology, Weill Cornell Medical College, New York, NY, U.S.A.
C HarwoodCentre for Cell Biology and Cutaneous Research, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, U.K.
S T ArronDepartment of Dermatology, University of California, San Francisco, CA, U.S.A.
S DemehriDepartment of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, U.S.A.
A GreenQIMR Berghofer Medical Research Institute, Brisbane, Qld, Australia.
M M AsgariDepartment of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, U.S.A.
NCI Keratinocyte Carcinoma Consortium
Massachusetts General Hospital · USCancer Research UK Manchester Institute · GBCornell University · USQueen Mary University of London · GBUniversity of California, San Francisco · US

Funding

Patient-oriented research and mentoring program in dermatologic diseasesK24AR069760 · NIAMS · UNIVERSITY OF COLORADO DENVER · PI ASGARI, MARYAM MANDANA · 2017 to 2025
$1.9M
Genome-wide association study of cutaneous squamous cell carincomaR01CA166672 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI ASGARI, MARYAM MANDANA · 2013 to 2016
$1.3M
NCI NIH HHS R01 CA166672NIAMS NIH HHS K24 AR069760
6 · The paper itself

Abstract

Although tremendous progress has been made in recent years in skin cancer care for organ transplant recipients, significant gaps remain in data-driven clinical guidelines, particularly for the treatment and prevention of cutaneous squamous cell carcinoma (cSCC), the most common malignancy among this population. In this review, we aim to summarize current knowledge around the management of cSCC and highlight the most significant gaps in knowledge that continue to pose challenges in the delivery of skin cancer care for organ transplant recipients. We suggest future directions for research that will bridge existing gaps and establish evidence-driven guidelines for primary prevention, screening and treatment of cSCC in this high-risk patient population.

Indexed as

Transplant RecipientsAntimetabolites, AntineoplasticCapecitabineCarcinoma, Squamous CellHealth BehaviorHumansImmunosuppression TherapyImmunosuppressive AgentsKeratoacanthomaNeoplasm MetastasisNiacinamideOrgan TransplantationPapillomavirus InfectionsPapillomavirus VaccinesPhotosensitivity DisordersQuality of LifeAntimetabolites, AntineoplasticCapecitabineImmunosuppressive AgentsNiacinamidePapillomavirus VaccinesRetinoidsVitamin B Complex

Identifiers

PMID29086412
PMCPMC5711582
OpenAlexW2765831284

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.