Evidence map›Paper›PMID 29086117›Full record

ArticleAIDS and behavior2018

Individual, Partner, and Couple Predictors of HIV Infection among Pregnant Women in Malawi: A Case-Control Study.

Nora E Rosenberg, Lauren A Graybill, Austin Wesevich, Nuala McGrath, Carol E Golin, Suzanne Maman, Mercy Tsidya, Limbikani Chimndozi, Irving F Hoffman, Mina C Hosseinipour and 1 more

Abstract read
In one paragraph

Article in AIDS and behavior, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Observational
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nora E RosenbergUNC Project, University of North Carolina at Chapel Hill, Lilongwe, Malawi. Nora_Rosenberg@unc.edu.ORCID http://orcid.org/0000-0002-9759-9966
Lauren A GraybillUNC Project, University of North Carolina at Chapel Hill, Lilongwe, Malawi.
Austin WesevichUNC Project, University of North Carolina at Chapel Hill, Lilongwe, Malawi.
Nuala McGrathFaculty of Medicine and Faculty of Social, Human, and Mathematical Sciences, University of Southampton, Southampton, England, UK.
Carol E GolinSchool of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Suzanne MamanSchool of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Mercy TsidyaUNC Project, University of North Carolina at Chapel Hill, Lilongwe, Malawi.
Limbikani ChimndoziUNC Project, University of North Carolina at Chapel Hill, Lilongwe, Malawi.
Irving F HoffmanUNC Project, University of North Carolina at Chapel Hill, Lilongwe, Malawi.
Mina C HosseinipourUNC Project, University of North Carolina at Chapel Hill, Lilongwe, Malawi.
William C MillerDepartment of Epidemiology, Ohio State University, Columbus, OH, USA.

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Option B+: ART Safety and Durability during First and Subsequent PregnanciesR01HD080485 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HOSSEINIPOUR, MINA CHRISTINE · 2014 to 2019
$3.9M
Training Program in Reproductive, Perinatal, and Pediatric EpidemiologyT32HD052468 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Julie L Daniels · 2008 to 2026
$3.8M
A dyad approach to combination HIV prevention in pregnancy for Zambia and MalawiR01AI131060 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CHI, BENJAMIN H., MUTALE, WILBROAD · 2017 to 2020
$2.7M
Developing and Assessing a Male Engagement Intervention for Option B+ in MalawiR00MH104154 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ROSENBERG, NORA · 2017 to 2019
$746k
Developing and Assessing a Male Engagement Intervention for Option B+ in MalawiK99MH104154 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ROSENBERG, NORA · 2015 to 2016
$168k
National Institute of Child Health and Human Development 4T32HD052468-09National Institute of Child Health and Human Development R01HD080485NIAID NIH HHS P30 AI050410NIAID NIH HHS R01 AI131060NICHD NIH HHS R01 HD080485NICHD NIH HHS T32 HD052468NIMH NIH HHS K99 MH104154NIMH NIH HHS K99/R00 MH104154NIMH NIH HHS R00 MH104154
6 · The paper itself

Abstract

We aimed to understand drivers of HIV-infection in pregnant women in Malawi. The study was conducted in antenatal and labor and delivery wards. HIV-infected women and their partners (cases) were frequency matched in a 1:2 ratio based on age and screening location to HIV-uninfected women and their partners (controls) in a prevalent case-control study. Characteristics associated with female HIV infection were assessed using logistic regression modeling. At screening, HIV-infected women were more likely to have partners outside Lilongwe than HIV-uninfected women (24% vs. 0%, p < 0.0001). Case females were more likely to have HIV-infected study partners than control females (75% vs. 4%, p < 0.0001). The odds of female HIV-infection were higher if either couple member reported ≥ 2 lifetime marriages (OR 9.0, CI 2.6-30.9) or ≥ 3 lifetime partners (OR 18.0, CI 3.1-103.6) and lower if either reported past couple HIV testing and counseling (OR 0.1, CI 0.04-0.3). Targeting women with migrating partners, promoting couple HIV testing and counseling, and limiting partners could slow HIV transmission.

Indexed as

AdultCase-Control StudiesCounselingFemaleHIV InfectionsHumansMalawiMaleMass ScreeningPregnancyPregnancy Complications, InfectiousPregnant PeopleSexual PartnersYoung AdultCounselingCoupleHIVPreventionRiskTesting

Identifiers

PMID29086117
PMCPMC5927853

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.