Evidence map›Paper›PMID 29086115›Full record

ReviewMedical oncology (Northwood, London, England)2017

Molecular imaging of advanced thyroid cancer: iodinated radiotracers and beyond.

Prasanna Santhanam, Lilja B Solnes, Steven P Rowe

Erratum issuedAbstract readReview
PubMed Publisher
In one paragraph

Review in Medical oncology (Northwood, London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Incremental diagnostic value of [European journal of nuclear medicine and molecular imaging · 2020
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Prasanna SanthanamDivision of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Johns Hopkins University School of Medicine, 1830 E. Monument St./Ste. 333, Baltimore, MD, 21287, USA. Psantha1@jhmi.edu.ORCID http://orcid.org/0000-0003-4822-2705
Lilja B SolnesSection of Nuclear Medicine, Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.
Steven P RoweSection of Nuclear Medicine, Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.
Johns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An important aspect of differentiated thyroid cancer (DTC) management is disease localization by imaging. Functional imaging of thyroid cancer with iodinated radiotracers has been employed for metastatic disease detection for long. More recently, 2-deoxy-2-[18F] fluoro-D-glucose (18F-FDG) positron emission tomography/computed tomography (PET/CT), a non-iodinated ubiquitous PET tracer, has been used to detect non-radioiodine (RAI) avid disease. Advances in molecular imaging have led to the development of newer tracers like 18F-TFB (18F-tetrafluoroborate) that are transported through the sodium-iodide symporter (NIS) as well as 68 Ga-DOTATATE that image the somatostatin receptors sub-type 2 expressed in medullary thyroid cancer and some DTC. In coming years, there will be focus on newer receptor targets like prostate-specific membrane antigen expression and endoradiotherapies and theranostics.

Indexed as

Antigens, SurfaceBoratesGlutamate Carboxypeptidase IIHumansIodine RadioisotopesMolecular ImagingOrganometallic CompoundsPositron Emission Tomography Computed TomographyPrecision MedicineRadiopharmaceuticalsSodium-Iodide SymportersSymportersThyroid NeoplasmsTomography, Emission-Computed, Single-PhotonAntigens, SurfaceBoratesfluoroboric acidFOLH1 protein, humangallium Ga 68 dotatateGlutamate Carboxypeptidase IIIodine RadioisotopesOrganometallic CompoundsRadiopharmaceuticalsSodium-Iodide SymportersSymportersDifferentiated Thyroid CancerImagingRadiotracers

Identifiers

PMID29086115
OpenAlexW2765423587

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.