Evidence map›Paper›PMID 29086110›Full record

ArticleFish physiology and biochemistry2018

Effect of follicle cell autophagy on gonadal development of triploid female rainbow trout (Oncorhynchus mykiss).

Tianqing Huang, Huizhi Sun, Yanna Wang, Gefeng Xu, Xingran Wang, Ying Han

Abstract read
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In one paragraph

Article in Fish physiology and biochemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Tianqing HuangDepartment of Animal Science and Technology, Northeast Agricultural University, Harbin, Heilongjiang, China.
Huizhi SunDepartment of Animal Science and Technology, Northeast Agricultural University, Harbin, Heilongjiang, China.
Yanna WangDepartment of Animal Science and Technology, Northeast Agricultural University, Harbin, Heilongjiang, China.
Gefeng XuNational and Local Joint Engineering Laboratory of Freshwater Fish Breeding, Heilongjiang Fisheries Research Institute, Chinese Academy of Fishery Sciences, Harbin, China.
Xingran WangDepartment of Animal Science and Technology, Northeast Agricultural University, Harbin, Heilongjiang, China.
Ying HanDepartment of Animal Science and Technology, Northeast Agricultural University, Harbin, Heilongjiang, China. hanying_606@163.com.
Northeast Agricultural University · CNChinese Academy of Fishery Sciences · CN

Funding

National Natural Science Foundation of China 31470131
6 · The paper itself

Abstract

Autophagy is a cellular process which occurs in eukaryotic cells. To study the mechanism regulating polyploid fish growth and development is of significance in genetic, because of its growth advantages and economic values. This study focused on triploid female rainbow trout (RBT) which discusses the effects of autophagy on gonadal development of polyploid fish. Autophagy-related genes of RBT lc3b, atg12, atg4b, gabarap1, and bcl2 were cloned, and autophagy gene expressions in gonads were analyzed at different developmental period. Gonadal ultrastructures were observed under transmission electron microscopy. To detect autophagy protein expression and localization, antibodies of RBT-LC3B and RBT-ATG12 were produced. Results showed clear evidence that autophagy-related genes were highly expressed during 200-300 days post fertilization (dpf), in which autophagosome structures were identified. In this stage, the conversion of LC3B-I to LC3B-II was greater than those in other stages. Immunolabeling-manifested autophagy occurred intensively in the cytoplasm of follicular cells. The morphology of follicular cells was gradually changed, leading to gonadal fibrosis and regression. This autophagic research is a new study area on gonadal development of polyploid fish.

Indexed as

TriploidyAnimalsAntibodiesAutophagyFemaleFish ProteinsGene Expression Regulation, DevelopmentalOncorhynchus mykissOvarian FollicleRecombinant ProteinsSex DifferentiationAntibodiesFish ProteinsRecombinant ProteinsAntibodyAutophagyLC3BRainbow troutTriploid

Identifiers

PMID29086110
OpenAlexW2765203063

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.