Evidence map›Paper›PMID 29086088›Full record

ReviewCurrent atherosclerosis reports2017

Emerging Associations Between Neutrophils, Atherosclerosis, and Psoriasis.

G E Sanda, A D Belur, H L Teague, Nehal N Mehta

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current atherosclerosis reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  15. Inflammatory Cells in Atherosclerosis.Antioxidants (Basel, Switzerland) · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

G E SandaCardiovascular and Pulmonary Branch, National Heart, Lung and Blood Institute, NIH, 10 Center Drive, CRC, Room 5-5140, Bethesda, MD, 20892, USA.
A D BelurCardiovascular and Pulmonary Branch, National Heart, Lung and Blood Institute, NIH, 10 Center Drive, CRC, Room 5-5140, Bethesda, MD, 20892, USA.
H L TeagueCardiovascular and Pulmonary Branch, National Heart, Lung and Blood Institute, NIH, 10 Center Drive, CRC, Room 5-5140, Bethesda, MD, 20892, USA.
Nehal N MehtaCardiovascular and Pulmonary Branch, National Heart, Lung and Blood Institute, NIH, 10 Center Drive, CRC, Room 5-5140, Bethesda, MD, 20892, USA. nehal.mehta@nih.gov.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewAtherogenesis, once thought to be a passive process, is now recognized as a dynamic, immune-driven process. The critical innate immune cells, including neutrophils, normal-density granulocytes, and their newly identified subset low-density granulocytes, are moving to the forefront of interest in cardiovascular medicine due to their abundance in atherosclerotic plaques and chronic inflammatory diseases associating with early cardiovascular disease (CVD) such as psoriasis. In this review, we discuss the emerging roles of neutrophils in CVD and how they play a potential role in early CVD observed in psoriasis patients. This review aims to describe the roles of neutrophils in both early atherosclerosis and psoriasis. RECENT

findingsRecent work has demonstrated mechanistic links between vascular inflammation and neutrophil frequency. Evolving mouse models and clinical trials targeting IL-17-associated pathways continue to elucidate contributions of neutrophils in both atherosclerosis and psoriasis. Early animal, in vitro and human studies suggest an important emerging role of neutrophils in atherosclerosis and psoriasis.

Indexed as

AnimalsAtherosclerosisCardiovascular DiseasesDisease Models, AnimalHumansInterleukin-17NeutrophilsPsoriasisInterleukin-17AtherosclerosisCardiovascular diseaseNeutrophilsPsoriasis

Identifiers

PMID29086088

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.