Evidence map›Paper›PMID 29085897›Full record

ArticleeNeuro

TU-Tagging: A Method for Identifying Layer-Enriched Neuronal Genes in Developing Mouse Visual Cortex.

Johanna Tomorsky, Leah DeBlander, Clifford G Kentros, Chris Q Doe, Cristopher M Niell

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Starve-Feed Cycles Direct Quiescence to Proliferation Transitions inbioRxiv : the preprint server for biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Johanna TomorskyInstitute of Neuroscience, University of Oregon, Eugene, OR 97403.ORCID 0000-0002-9392-1874
Leah DeBlanderInstitute of Neuroscience, University of Oregon, Eugene, OR 97403.
Clifford G KentrosInstitute of Neuroscience, University of Oregon, Eugene, OR 97403.
Chris Q DoeInstitute of Neuroscience, University of Oregon, Eugene, OR 97403.ORCID 0000-0001-5980-8029
Cristopher M NiellInstitute of Neuroscience, University of Oregon, Eugene, OR 97403.
University of Oregon · USHoward Hughes Medical Institute · US

Funding

DEVELOPMENTAL BIOLOGY TRAINING PROGRAMT32HD007348 · NICHD · UNIVERSITY OF OREGON · PI Chris Q Doe, KRYN STANKUNAS · 1989 to 2026
$6.8M
Genetic and Molecular Studies of NeurogenesisR37HD027056 · NICHD · UNIVERSITY OF OREGON · PI DOE, CHRIS Q · 2012 to 2021
$3.0M
Connecting developmental mechanisms to visual function and perceptionDP2EY023190 · NEI · UNIVERSITY OF OREGON · PI NIELL, CRISTOPHER M · 2012 to 2012
$2.2M
Neural pathways and behavioral state in the visual systemR01EY023337 · NEI · UNIVERSITY OF OREGON · PI NIELL, CRISTOPHER M · 2013 to 2017
$1.8M
Howard Hughes Medical InstituteNICHD NIH HHS T32 HD007348
6 · The paper itself

Abstract

Thiouracil (TU)-tagging is an intersectional method for covalently labeling newly transcribed RNAs within specific cell types. Cell type specificity is generated through targeted transgenic expression of the enzyme uracil phosphoribosyl transferase (UPRT); temporal specificity is generated through a pulse of the modified uracil analog 4TU. This technique has been applied in mouse using a Cre-dependent UPRT transgene,

Indexed as

Mice, TransgenicThiouracilAnimalsDermoscopyFemaleGene Expression ProfilingGene Expression Regulation, DevelopmentalImmunohistochemistryIn Situ HybridizationMaleNeuronsRNA, MessengerTranscriptomeVisual CortexRNA, MessengerThiouracilgene expressionlayer 2/3postnataltranscriptomicsTU-taggingvisual cortex

Identifiers

PMID29085897
PMCPMC5659240
OpenAlexW2755154112

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.