Evidence map›Paper›PMID 29085678›Full record

Trial reportJournal of pregnancy2017

The Routine Use of Prophylactic Oxytocin in the Third Stage of Labor to Reduce Maternal Blood Loss.

Akiko Kuzume, So Sugimi, Sachie Suga, Hiroshi Yamashita, Ichiro Yasuhi

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Journal of pregnancy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Akiko KuzumeDepartment of Obstetrics and Gynecology, NHO Nagasaki Medical Center, Omura, Japan.
So SugimiDepartment of Obstetrics and Gynecology, NHO Nagasaki Medical Center, Omura, Japan.
Sachie SugaDepartment of Obstetrics and Gynecology, NHO Nagasaki Medical Center, Omura, Japan.
Hiroshi YamashitaDepartment of Obstetrics and Gynecology, NHO Nagasaki Medical Center, Omura, Japan.
Ichiro YasuhiDepartment of Obstetrics and Gynecology, NHO Nagasaki Medical Center, Omura, Japan.ORCID 0000-0002-0350-5130
Nagasaki Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo demonstrate whether or not the routine use of prophylactic oxytocin (RUPO) reduces the blood loss and incidence of postpartum hemorrhaging (PPH).

methodsWe used a prospective cohort and a historical control in a tertiary perinatal care center in Japan. In the prospective cohort, we introduced RUPO in April 2012 by infusing 10 units of oxytocin per 500 mL of normal saline into a venous line after anterior shoulder delivery (RUPO group). In the historical control, oxytocin was administered via a case-selective approach (historical control group). We included completed singleton vaginal deliveries and compared the volume of blood loss and the incidence of PPH between the groups.

resultsWe found a significantly lower volume of blood loss (520 ± 327 versus 641 ± 375 mL,

conclusionsThe introduction of RUPO significantly reduced blood loss and the incidence of PPH during completed singleton vaginal deliveries without an increase in adverse effects.

Indexed as

Labor Stage, ThirdAdultDrug Administration ScheduleFemaleHumansIncidenceOxytocicsOxytocinPostpartum HemorrhagePregnancyProspective StudiesTreatment OutcomeOxytocicsOxytocin

Identifiers

PMID29085678
PMCPMC5611883
OpenAlexW2753963717

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.