Evidence map›Paper›PMID 29085667›Full record

ArticleThe journal of pathology. Clinical research2017

Histopathological and genotypic characterization of metastatic colorectal carcinoma with PD-L1 (CD274)-expression: Possible roles of tumour micro environmental factors for CD274 expression.

Shingo Inaguma, Jerzy Lasota, Anna Felisiak-Golabek, Artur Kowalik, Zengfeng Wang, Sebastian Zieba, Joanna Kalisz, Hiroshi Ikeda, Markku Miettinen

Open access · goldAbstract read
In one paragraph

Article in The journal of pathology. Clinical research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 21 citations in OpenAlex.

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  6. Inverse relationship betweenClinical & translational immunology · 2023
    Article
  7. PBK expression predicts favorable survival in colorectal cancer patients.Virchows Archiv : an international journal of pathology · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Shingo InagumaLaboratory of PathologyNational Cancer InstituteBethesdaMDUSA.ORCID 0000-0001-8585-8900
Jerzy LasotaLaboratory of PathologyNational Cancer InstituteBethesdaMDUSA.
Anna Felisiak-GolabekLaboratory of PathologyNational Cancer InstituteBethesdaMDUSA.
Artur KowalikDepartment of Molecular DiagnosticsHolycross Cancer CenterKielcePoland.
Zengfeng WangLaboratory of PathologyNational Cancer InstituteBethesdaMDUSA.
Sebastian ZiebaDepartment of Molecular DiagnosticsHolycross Cancer CenterKielcePoland.
Joanna KaliszDepartment of Molecular DiagnosticsHolycross Cancer CenterKielcePoland.
Hiroshi IkedaDepartment of PathologyAichi Medical University School of MedicineNagakuteAichiJapan.
Markku MiettinenLaboratory of PathologyNational Cancer InstituteBethesdaMDUSA.
National Cancer Institute · USHoly Cross University · PLAichi Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aberrant PD-L1 (CD274) expression has been described in different types of tumour and linked to tumour aggressiveness and a poor prognosis. In primary colorectal carcinomas (CRCs), CD274 expression was reported to be associated with mismatch repair (MMR)-deficiency,

Indexed as

ALCAM (CD166)BRAFCD274 (PD‐L1)CDX2IFNγimmunohistochemistryKRASmetastatic colorectal carcinomaTGF‐β1

Identifiers

PMID29085667
PMCPMC5653930
OpenAlexW2751467081

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.