Evidence map›Paper›PMID 29085524›Full record

ArticleBiomicrofluidics2017

A compact microfluidic chip with integrated impedance biosensor for protein preconcentration and detection.

Tuan Vu Quoc, Meng-Syuan Wu, Tung Thanh Bui, Trinh Chu Duc, Chun-Ping Jen

Abstract read
In one paragraph

Article in Biomicrofluidics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 13 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Tuan Vu QuocInstitute of Applied Physics and Scientific Instrument, Vietnam Academy of Science and Technology, Hanoi, Vietnam.ORCID 0000-0002-2005-0721
Meng-Syuan WuDepartment of Mechanical Engineering, National Chung Cheng University, Chia-Yi, Taiwan.
Tung Thanh BuiUniversity of Engineering and Technology, Vietnam National University, Hanoi, Vietnam.ORCID 0000-0003-4628-059X
Trinh Chu DucUniversity of Engineering and Technology, Vietnam National University, Hanoi, Vietnam.
Chun-Ping JenDepartment of Mechanical Engineering, National Chung Cheng University, Chia-Yi, Taiwan.
National Chung Cheng University · TWVietnam Academy of Science and Technology · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, a low-cost, compact biochip is designed and fabricated for protein detection. Nanofractures formed by self-assembled gold nanoparticles at junction gaps are applied for ion enrichment and depletion to create a trapping zone when electroosmotic flow occurs in microchannels. An impedance measurement module is implemented based on the lock-in amplifier technique to measure the impedance change during antibody growth on the gold electrodes which is caused by trapped proteins in the detection region. The impedance measurement results confirm the presence of trapped proteins. Distinguishable impedance profiles, measured at frequencies in the range of 10-100 kHz, for the detection area taken before and after the presence of proteins validate the performance of the proposed system.

Identifiers

PMID29085524
PMCPMC5653376
OpenAlexW2766037823

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.