Evidence map›Paper›PMID 29085432›Full record

ArticleInternational journal of pediatrics2017

The Fatty Acid Profile in Patients with Newly Diagnosed Diabetes: Why It Could Be Unsuspected.

C Castro-Correia, S Sousa, S Norberto, C Matos, V F Domingues, M Fontoura, C Calhau

Abstract read
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Article in International journal of pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Nutritional Values of Teff (Diabetes, metabolic syndrome and obesity : targets and therapy · 2022
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

C Castro-CorreiaUnidade de Endocrinologia Pediátrica, Hospital Pediátrico Integrado, Centro Hospitalar S. João, Faculty of Medicine, University of Porto, 4200 Porto, Portugal.ORCID 0000-0002-5967-0231
S SousaREQUIMTE/LAQV-GRAQ, Instituto Superior de Engenharia do Porto, Instituto Politécnico do Porto, 4200-072 Porto, Portugal.
S NorbertoDepartment of Biochemistry, Faculty of Medicine, University of Porto, Centro de Investigação Médica, 4200-450 Porto, Portugal.
C MatosCenter for Research in Health Technologies and Information Systems (CINTESIS), 4200-450 Porto, Portugal.
V F DominguesREQUIMTE/LAQV-GRAQ, Instituto Superior de Engenharia do Porto, Instituto Politécnico do Porto, 4200-072 Porto, Portugal.ORCID 0000-0003-3472-849X
M FontouraUnidade de Endocrinologia Pediátrica, Hospital Pediátrico Integrado, Centro Hospitalar S. João, Faculty of Medicine, University of Porto, 4200 Porto, Portugal.
C CalhauDepartment of Biochemistry, Faculty of Medicine, University of Porto, Centro de Investigação Médica, 4200-450 Porto, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextSeveral studies have shown a link between proinflammatory activity and the presence or deficit of some fatty acids. Inflammation is associated with several diseases including diabetes.

objectiveTo characterize and compare the fatty acids profiles in children with inaugural type 1 diabetes, diabetic children (at least 1 year after diagnosis), and healthy children.

designPlasma fatty acids profiles in children with inaugural diabetes, children with noninaugural diabetes, and controls, all of whom were prepubescent with a BMI < 85th percentile, were evaluated.

resultsOmega-3 fatty acid levels were higher in recently diagnosed subjects with diabetes than in controls. The ratio of omega-6/omega-3 fatty acids was higher in the control population. Omega-6 fatty acid levels were higher in the nonrecent diabetic subjects than in the children with recently diagnosed diabetes, and the levels were higher in the nonrecent diabetes group compared to the control group.

conclusionOur findings showed higher levels of alpha-linolenic acid, EPA, and DHA, as well as mono- and polyunsaturated fatty acids, in diabetic children. These findings reinforce the importance of precocious nutritional attention and intervention in the treatment of diabetic children.

Identifiers

PMID29085432
PMCPMC5611882

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.