Evidence map›Paper›PMID 29085406›Full record

ArticleAfrican health sciences2017

Anti-mycobacterium tuberculosis activity of polyherbal medicines used for the treatment of tuberculosis in Eastern Cape, South Africa.

Elizabeth B Famewo, Anna M Clarke, Ian Wiid, Andile Ngwane, Paul van Helden, Anthony J Afolayan

Abstract readEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in African health sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elizabeth B FamewoFaculty of Science and Agriculture, University of Fort Hare, Alice 5700, South Africa.
Anna M ClarkeFaculty of Science and Agriculture, University of Fort Hare, Alice 5700, South Africa.
Ian WiidDST-NRF Centre of Excellence for Biomedical Tuberculosis Research, SAMRC Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, PO Box 241, Cape Town 8000, South Africa.
Andile NgwaneDST-NRF Centre of Excellence for Biomedical Tuberculosis Research, SAMRC Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, PO Box 241, Cape Town 8000, South Africa.
Paul van HeldenDST-NRF Centre of Excellence for Biomedical Tuberculosis Research, SAMRC Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, PO Box 241, Cape Town 8000, South Africa.
Anthony J AfolayanFaculty of Science and Agriculture, University of Fort Hare, Alice 5700, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe emergence of drug-resistant strains of

objectiveTo evaluate the anti-tubercular activity of polyherbal medicines used for the treatment of tuberculosis.

methodsThe remedies were screened against

resultsThe susceptibility testing revealed that all the remedies contain anti-tubercular activity with KWTa, KWTb, KWTc, HBfs, HBts, AL and FB exhibiting more activity at a concentration below 25 µl/ml. Furthermore, MIC values exhibited inhibitory activity with the most active remedies from KWTa, HBfs and HBts at 1.562 µg/ml. However, isoniazid showed more inhibitory activity against

conclusionThis study has indicated that these remedies could be potential sources of new anti-mycobacterial agents against

Indexed as

Drug ContaminationPhytotherapyAntitubercular AgentsHumansIsoniazidMicrobial Sensitivity TestsMycobacterium tuberculosisPlant ExtractsPlants, MedicinalSouth AfricaTuberculosisAntitubercular AgentsIsoniazidPlant Extractsin vitro activityMycobacterium tuberculosispolyherbal medicinesSouth Africa

Identifiers

PMID29085406
PMCPMC5656206

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.