Evidence map›Paper›PMID 29085392›Full record

ArticleAfrican health sciences2017

Contribution of IgG avidity and PCR for the early diagnosis of toxoplasmosis in pregnant women from the North-Eastern region of Algeria.

Hajira Berredjem, Hayette Aouras, Meriem Benlaifa, Imène Becheker, Mohamed Reda Djebar

Abstract readComparative Study
In one paragraph

Article in African health sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hajira BerredjemDepartment of Biochemistry, Faculty of Sciences, University of Badji Mokhtar, Annaba, Algeria.
Hayette AourasService of Gynecology, EHS Abdallah Nouaouria Hospital, El Bouni-Annaba, Algeria.
Meriem BenlaifaLaboratory of Cellular Toxicology, Faculty of Sciences, University of Badji Mokhtar, Annaba, Algeria.
Imène BechekerDepartment of Biochemistry, Faculty of Sciences, University of Badji Mokhtar, Annaba, Algeria.
Mohamed Reda DjebarLaboratory of Cellular Toxicology, Faculty of Sciences, University of Badji Mokhtar, Annaba, Algeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute toxoplasmosis in pregnant women presents a high risk of

objectivesThe aim of this study was to compare conventional ELISA and IgG avidity, with PCR using B1 and P30 primers for the early diagnosis of toxoplasmosis in pregnant women.

methodsSera were collected from 143 pregnant women and measured by ELISA for anti-

resultsA total of 57 out 143 women were seropositive: 30 (52.6%) were IgG+/IgM- and 27 (43.8%) were IgG+/IgM+; IgA antibodies were positive in 7 (12.2%) cases. IgG avidity was low in 9 women suggesting an acute infection; 3 women presented an intermediate avidity. PCR detected

conclusionPCR combined to avidity IgG performed better than ELISA IgG, IgM and/or IgA assays alone. PCR was useful in the case of intermediate avidity.

Indexed as

AdultAlgeriaAmniotic FluidAntibodies, ProtozoanAntibody AffinityDNA, ProtozoanEnzyme-Linked Immunosorbent AssayFemaleHumansImmunoglobulin AImmunoglobulin GImmunoglobulin MNucleic Acid Amplification TechniquesPolymerase Chain ReactionPredictive Value of TestsPregnancyAntibodies, ProtozoanDNA, ProtozoanImmunoglobulin AImmunoglobulin GImmunoglobulin MIgG avidityPCRpregnant womenserologyToxoplasmosis

Identifiers

PMID29085392
PMCPMC5656190

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.