Evidence map›Paper›PMID 29085277›Full record

ReviewFrontiers in neuroscience2017

Social Context, Stress, Neuropsychiatric Disorders, and the Vasopressin 1b Receptor.

Heather K Caldwell, Elizabeth A Aulino, Karla M Rodriguez, Shannah K Witchey, Alexandra M Yaw

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.

  1. Pooled it
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  15. Complementary Role of Oxytocin and Vasopressin in Cardiovascular Regulation.International journal of molecular sciences · 2021
    Review
  16. Article
  17. Review
  18. The Biology of Vasopressin.Biomedicines · 2021
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Heather K CaldwellLaboratory of Neuroendocrinology and Behavior, Department of Biological Sciences Kent State University, Kent, OH, United States.
Elizabeth A AulinoLaboratory of Neuroendocrinology and Behavior, Department of Biological Sciences Kent State University, Kent, OH, United States.
Karla M RodriguezSchool of Biomedical Sciences, Kent State University, Kent, OH, United States.
Shannah K WitcheyLaboratory of Neuroendocrinology and Behavior, Department of Biological Sciences Kent State University, Kent, OH, United States.
Alexandra M YawSchool of Biomedical Sciences, Kent State University, Kent, OH, United States.
Kent State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The arginine vasopressin 1b receptor (Avpr1b) is involved in the modulation of a variety of behaviors and is an important part of the mammalian hormonal stress axis. The Avpr1b is prominent in hippocampal CA2 pyramidal cells and in the anterior pituitary corticotrophs. Decades of research on this receptor has demonstrated its importance to the modulation of social recognition memory, social forms of aggression, and modulation of the hypothalamic-pituitary-adrenal axis, particularly under conditions of acute stress. Further, work in humans suggests that the Avpr1b may play a role in human neuropsychiatric disorders and its modulation may have therapeutic potential. This paper reviews what is known about the role of the Avpr1b in the context of social behaviors, the stress axis, and human neuropsychiatric disorders. Further, possible mechanisms for how Avpr1b activation within the hippocampus vs. Avpr1b activation within anterior pituitary may interact with one another to affect behavioral output are proposed.

Indexed as

aggressionanimal modelshormonal stress responseneuropsychiatric disorderssocial recognition memory

Identifiers

PMID29085277
PMCPMC5650633
OpenAlexW2767051484

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.