Evidence map›Paper›PMID 29085234›Full record

ArticleWorld journal of gastroenterology2017

Persistent severe hypomagnesemia caused by proton pump inhibitor resolved after laparoscopic fundoplication.

Synne Semb, Frederik Helgstrand, Flemming Hjørne, Peter Bytzer

Open access · hybridAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Synne SembDepartment of Gastroenterology, Zealand University Hospital, 4600 Køge, Denmark. sys@regionsjaelland.dk.
Frederik HelgstrandDepartment of Surgery, Zealand University Hospital, 4600 Køge, Denmark.
Flemming HjørneDepartment of Surgery, Zealand University Hospital, 4600 Køge, Denmark.
Peter BytzerDepartment of Gastroenterology, Zealand University Hospital, 4600 Køge, Denmark.
Zealand University Hospital Køge · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnesium deficiency can cause a variety of symptoms, including potentially life-threatening complications such as seizures, cardiac arrhythmias and secondary electrolyte disturbances. Hypomagnesemia can be a serious adverse effect to proton pump inhibitor (PPI) therapy, which is worrying due to the widespread use of PPIs. Current evidence suggest that the mechanism of PPI induced hypomagnesemia is impaired intestinal magnesium absorption. In this report, we present the case of a long-term PPI user with persistent hypomagnesemia with severe symptoms at presentation. He was unable to stop PPI treatment because of severe reflux symptoms, and was dependent on weekly intravenous magnesium infusions, until his magnesium levels finally normalized without the need for supplementation after a successful laparoscopic fundoplication.

Indexed as

Administration, OralAgedFundoplicationGastroesophageal RefluxHumansInfusions, IntravenousIntestinal AbsorptionLaparoscopyMagnesiumMagnesium DeficiencyMaleOmeprazoleProton Pump InhibitorsSeizuresVomitingWater-Electrolyte ImbalanceMagnesiumOmeprazoleProton Pump InhibitorsDrug adverse effectGastroesophageal reflux diseaseHypomagnesemiaLaparoscopic fundoplicationProton pump inhibitor

Identifiers

PMID29085234
PMCPMC5645624
OpenAlexW2758224593

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.