ArticleWorld journal of gastroenterology2017
Effect of local wound infiltration with ropivacaine on postoperative pain relief and stress response reduction after open hepatectomy.
Article in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- Use of local wound infiltration in open hepatectomy to reduce wound pain: A systematic review and meta-analysis.International wound journal · 2023Pooled it
- Guidelines for Perioperative Care for Liver Surgery: Enhanced Recovery After Surgery (ERAS) Society Recommendations 2022.World journal of surgery · 2023Pooled it
- Efficacy of dexmedetomidine as an adjuvant to local wound infiltration anaesthesia in abdominal surgery: A meta-analysis of randomised controlled trials.International wound journal · 2019Pooled it
- The combination of transversus abdominis plane block and rectus sheath block reduced postoperative pain after splenectomy: a randomized trial.BMC anesthesiology · 2020Trial
- Overlay of a sponge soaked with ropivacaine and multisite infiltration analgesia result in faster recovery after laparoscopic hepatectomy.World journal of gastroenterology · 2019Trial
- Article
- Updates on Wound Infiltration Use for Postoperative Pain Management: A Narrative Review.Journal of clinical medicine · 2021Review
- Postoperative Analgesia after Open Liver Surgery: Systematic Review of Clinical Evidence.Journal of clinical medicine · 2021Review
- Pain management after open liver resection: Procedure-Specific Postoperative Pain Management (PROSPECT) recommendations.Regional anesthesia and pain medicine · 2021Review
- Analgesic effect of parecoxib combined with ropivacaine in patients undergoing laparoscopic hepatectomy.World journal of clinical cases · 2019Article
- Local Wound Infiltration with Ropivacaine for Postoperative Pain Control in Caesarean Section.Cureus · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo prospectively evaluate the effect of local wound infiltration with ropivacaine on postoperative pain relief and stress response reduction after open hepatectomy.
methodsA total of 56 patients undergoing open hepatectomy were randomly divided into two groups: a ropivacaine group (wound infiltration with ropivacaine solution) and a control group (infiltration with isotonic saline solution). A visual analog scale (VAS) at rest and on movement was used to measure postoperative pain for the first 48 h after surgery. Mean arterial pressure (MAP), heart rate (HR), time to bowel recovery, length of hospitalization after surgery, cumulative sufentanil consumption, and incidence of nausea and vomiting were compared between the two groups. Surgical stress hormones (epinephrine, norepinephrine, and cortisol) were detected using enzyme-linked immunosorbent assay, and the results were compared.
resultsVAS scores both at rest and on movement at 24 h and 48 h were similar between the two groups. Significantly lower VAS scores were detected at 0, 6, and 12 h in the ropivacaine group compared with the control group (
conclusionLocal wound infiltration with ropivacaine after open hepatectomy can improve postoperative pain relief, reduce surgical stress response, and accelerate postoperative recovery.
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Registered trials
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