Evidence map›Paper›PMID 29084985›Full record

ArticleScientific reports2017

Leishmania infantum lipophosphoglycan induced-Prostaglandin E

Jonilson Berlink Lima, Théo Araújo-Santos, Milena Lázaro-Souza, Alan Brito Carneiro, Izabela Coimbra Ibraim, Flávio Henrique Jesus-Santos, Nívea Farias Luz, Sara de Moura Pontes, Petter Franco Entringer, Albert Descoteaux and 3 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Fatty Acid Composition and Metabolism inInternational journal of molecular sciences · 2023
    Review
  6. Elucidating the role played by bone marrow in visceral leishmaniasis.Frontiers in cellular and infection microbiology · 2023
    Review
  7. Review
  8. Lipophosphoglycan From Dermotropic New WorldFrontiers in cellular and infection microbiology · 2022
    Article
  9. Article
  10. Review
  11. Article
  12. Crosstalk between Metabolic Disorders and Immune Cells.International journal of molecular sciences · 2021
    Review
  13. Article
  14. Insights intoVeterinary sciences · 2021
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Jonilson Berlink LimaGonçalo Moniz Institut, Oswaldo Cruz Foundation (FIOCRUZ-BA), 40296-710, Salvador, BA, Brazil.
Théo Araújo-SantosGonçalo Moniz Institut, Oswaldo Cruz Foundation (FIOCRUZ-BA), 40296-710, Salvador, BA, Brazil.ORCID 0000-0001-9861-6660
Milena Lázaro-SouzaGonçalo Moniz Institut, Oswaldo Cruz Foundation (FIOCRUZ-BA), 40296-710, Salvador, BA, Brazil.
Alan Brito CarneiroLaboratory of Immunopharmacology, Oswaldo Cruz Institut, FIOCRUZ-RJ, 21040-900, Rio de Janeiro, RJ, Brazil.
Izabela Coimbra IbraimRené Rachou Institut, Oswaldo Cruz Foundation (FIOCRUZ-MG), 30190-002, Belo Horizonte, MG, Brazil.
Flávio Henrique Jesus-SantosGonçalo Moniz Institut, Oswaldo Cruz Foundation (FIOCRUZ-BA), 40296-710, Salvador, BA, Brazil.
Nívea Farias LuzGonçalo Moniz Institut, Oswaldo Cruz Foundation (FIOCRUZ-BA), 40296-710, Salvador, BA, Brazil.
Sara de Moura PontesGonçalo Moniz Institut, Oswaldo Cruz Foundation (FIOCRUZ-BA), 40296-710, Salvador, BA, Brazil.
Petter Franco EntringerFederal University of Rio de Janeiro (UFRJ), NUPEM, Campus Macaé, 27933-378, Macaé, RJ, Brazil.
Albert DescoteauxInstitut National de la Recherche Scientifique, Institut Armand-Frappier, H7V 1B7, Laval, Canada.
Patrícia Torres BozzaLaboratory of Immunopharmacology, Oswaldo Cruz Institut, FIOCRUZ-RJ, 21040-900, Rio de Janeiro, RJ, Brazil.
Rodrigo Pedro SoaresRené Rachou Institut, Oswaldo Cruz Foundation (FIOCRUZ-MG), 30190-002, Belo Horizonte, MG, Brazil. rsoares@cpqrr.fiocruz.br.
Valéria Matos BorgesGonçalo Moniz Institut, Oswaldo Cruz Foundation (FIOCRUZ-BA), 40296-710, Salvador, BA, Brazil. vborges@bahia.fiocruz.br.ORCID 0000-0002-2775-5409
Fundação Oswaldo Cruz · BRUniversidade Federal da Bahia · BRUniversidade Federal do Oeste da Bahia · BRInstitut National de la Recherche Scientifique · CAUniversidade Federal do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipophosphoglycan (LPG) is a key virulence factor expressed on the surfaces of Leishmania promastigotes. Although LPG is known to activate macrophages, the underlying mechanisms resulting in the production of prostaglandin E

Indexed as

AnimalsCells, CulturedDinoprostoneGene Expression RegulationGlycosphingolipidsLeishmania infantumLeishmaniasis, VisceralMacrophagesMaleMiceMice, Inbred C57BLPPAR gammaToll-Like Receptor 1Toll-Like Receptor 2Virulence FactorsDinoprostoneGlycosphingolipidslipophosphonoglycanPPAR gammaToll-Like Receptor 1Toll-Like Receptor 2Virulence Factors

Identifiers

PMID29084985
PMCPMC5662570
OpenAlexW2765718728

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.