Evidence map›Paper›PMID 29084844›Full record

ArticleThe Journal of biological chemistry2017

Role of lysosomal channel protein TPC2 in osteoclast differentiation and bone remodeling under normal and low-magnesium conditions.

Takuya Notomi, Miyuki Kuno, Akiko Hiyama, Tadashige Nozaki, Kiyoshi Ohura, Yoichi Ezura, Masaki Noda

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Membrane Transport Proteins in Osteoclasts: The Ins and Outs.Frontiers in cell and developmental biology · 2021
    Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Takuya NotomiFrom the Department of Molecular Pharmacology, Medical Research Institute and notomi@cc.osaka-dent.ac.jp.
Miyuki Kunothe Department of Physiology, Graduate School of Medicine, Osaka City University, Abeno, Osaka 545-8585, Japan, and.
Akiko Hiyamathe Department of Pharmacology, Osaka Dental University, Hirakata, Osaka 573-1121, Japan.
Tadashige Nozakithe Department of Pharmacology, Osaka Dental University, Hirakata, Osaka 573-1121, Japan.
Kiyoshi Ohurathe Department of Pharmacology, Osaka Dental University, Hirakata, Osaka 573-1121, Japan.
Yoichi EzuraFrom the Department of Molecular Pharmacology, Medical Research Institute and.
Masaki NodaFrom the Department of Molecular Pharmacology, Medical Research Institute and noda.mph@mri.tmd.ac.jp.
Osaka Dental University · JPTokyo Medical and Dental University · JPOsaka City University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The bone is the main storage site for Ca

Indexed as

AnimalsBone RemodelingBone ResorptionCalcium ChannelsCalcium SignalingCell DifferentiationInositolLysosomesMagnesiumMagnesium DeficiencyMaleMembrane PotentialsMiceMice, Inbred C57BLOsteoclastsOsteogenesisCalcium ChannelsInositolMagnesiumphosphatidylinositol 3,5-diphosphatePhosphatidylinositol PhosphatesSodiumTPCN2 protein, mouseion channellysosomemagnesiumoptogeneticsosteoclastphosphatidylinositol phosphataseplasma membrane

Identifiers

PMID29084844
PMCPMC5743074
OpenAlexW2766089757

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.