Observational studyBMJ open2017
Associations of adiposity measurements with thyroid nodules in Chinese children living in iodine-sufficient areas: an observational study.
Observational study in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Correlations between iodine status and the risk of thyroid nodules, a systematic review and dose-response meta-analysis.Frontiers in endocrinology · 2026Pooled it
- Adiposity Is Associated with a Higher Risk of Thyroid Malignancy in Patients with Hashimoto's Thyroiditis.Diagnostics (Basel, Switzerland) · 2025Article
- Effects of Overweight on Risk of Thyroid Nodules in Children and Adolescents: The Fukushima Health Management Survey.The Journal of clinical endocrinology and metabolism · 2025Article
- Association of gender and metabolic factors with thyroid nodules in T2DM: a retrospective study.PeerJ · 2025Article
- Article
- Analysis of Body Mass Index and Clinicopathological Factors in Patients with Papillary Thyroid Carcinoma.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Article
- Risk factors associated with the prevalence of thyroid nodules in adults in Northeast China: a cross-sectional population-based study.BMJ open · 2023Article
- Thyroid Nodules and Obesity.Life (Basel, Switzerland) · 2023Review
- Regional Disparities in Obesity Among a Heterogeneous Population of Chinese Children and Adolescents.JAMA network open · 2021Article
- The association between BMI, smoking, drinking and thyroid disease: a cross-sectional study in Wuhan, China.BMC endocrine disorders · 2021Article
- Body Habitus Across the Lifespan and Risk of Pituitary Adenoma.The Journal of clinical endocrinology and metabolism · 2021Article
- Iodine nutrition and prevalence of sonographic thyroid findings in adults in the Heilongjiang Province, China.Annals of translational medicine · 2020Article
- Thyroid Stimulating Hormone (TSH) Is Associated With General and Abdominal Obesity: A Cohort Study in School-Aged Girls During Puberty in East China.Frontiers in endocrinology · 2020Article
- Adiposity and the risk of thyroid nodules with a high-suspicion sonographic pattern: a large cross-sectional epidemiological study.Journal of thoracic disease · 2019Article
- Optimal levothyroxine dose in post-total thyroidectomy patients: a prediction model for initial dose titration.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesObesity has been found to be associated with an elevated risk of thyroid nodule(s), mainly in adults; however, evidence for this association in children was limited. The objective of this study was to investigate the association of adiposity and thyroid nodule(s) in children living in iodine-sufficiency areas. SETTING AND
participantsWe conducted a cross-sectional study of 1403 Chinese children living in the East Coast of China in 2014. OUTCOME MEASURES: Anthropometric measures including height, weight and waist and hip circumferences were taken, and body mass index (BMI), body surface area (BSA) and waist-hip ratio (WHR) were then calculated. Thyroid ultrasonography was performed to assess thyroid volume and nodules.
resultsBased on BMI, 255 (18.17%) children were overweight and 174 (12.40%) were obese. Thyroid nodule(s) was detected in 18.46% of all participants and showed little age and sex variations. As compared with normal-weight children, obese children experienced significantly higher risks for solitary (OR 2.07 (95% CI 1.16 to 3.71)) and multiple (OR 1.67 (95% CI 1.03 to 2.70)) thyroid nodules. Similar associations with thyroid nodule(s) were observed with adiposity measured by waist circumference and BSA, but not WHR. There were no notable differences in the associations between children consuming iodised and non-iodised salt.
conclusionsThese findings provide further evidence that childhood obesity is associated with the risk for thyroid nodule(s).
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