ArticleBMC plant biology2017
A cadmium stress-responsive gene AtFC1 confers plant tolerance to cadmium toxicity.
Article in BMC plant biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21 citing papers in PubMed, 100 citations in OpenAlex.
- Evaluation of the genes CYPEnvironmental science and pollution research international · 2026Article
- Comparative physiological and transcriptomic analyses reveal different stress adaptation strategies controlling buckwheat chilling tolerance.BMC plant biology · 2025Article
- Cadmium Stress Signaling Pathways in Plants: Molecular Responses and Mechanisms.Current issues in molecular biology · 2024Review
- The Uptake, Transfer, and Detoxification of Cadmium in Plants and Its Exogenous Effects.Cells · 2024Review
- Cadmium and copper-induced metabolic and proteomic changes in the root tip during early maize growth.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024Article
- In-depth comparative transcriptome analysis of Purpureocillium sp. CB1 under cadmium stress.Applied microbiology and biotechnology · 2023Article
- Unraveling the Mechanism of StWRKY6 in Potato (Foods (Basel, Switzerland) · 2023Article
- Leaf Color Classification and Expression Analysis of Photosynthesis-Related Genes in Inbred Lines of Chinese Cabbage Displaying Minor Variations in Dark-Green Leaves.Plants (Basel, Switzerland) · 2023Article
- The Effect of Cadmium on Plants in Terms of the Response of Gene Expression Level and Activity.Plants (Basel, Switzerland) · 2023Review
- Identification of a DEAD-box RNA Helicase BnRH6 Reveals Its Involvement in Salt Stress Response in Rapeseed (International journal of molecular sciences · 2022Article
- Plants grown in Apollo lunar regolith present stress-associated transcriptomes that inform prospects for lunar exploration.Communications biology · 2022Article
- Cotton straw biochar and compoundFrontiers in plant science · 2022Article
- RNA-Seq Identification of Cd Responsive Transporters Provides Insights into the Association of Oxidation Resistance and Cd Accumulation inAntioxidants (Basel, Switzerland) · 2021Article
- Enzymatic response to cadmium byBiochemistry and biophysics reports · 2021Article
- CAX3 (cation/proton exchanger) mediates a Cd tolerance by decreasing ROS through Ca elevation in Arabidopsis.Plant molecular biology · 2021Article
- WDR5a functions in cadmium-inhibited root meristem growth by regulating nitric oxide accumulation in Arabidopsis.Planta · 2020Article
- Anatomic features, tolerance index, secondary metabolites and protein content of chickpea (Physiology and molecular biology of plants : an international journal of functional plant biology · 2020Article
- Review
- Article
- Cadmium toxicity degree on tomato development is associated with disbalances in B and Mn status at early stages of plant exposure.Ecotoxicology (London, England) · 2018Article
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNon-essential trance metal such as cadmium (Cd) is toxic to plants. Although some plants have developed elaborate strategies to deal with absorbed Cd through multiple pathways, the regulatory mechanisms behind the Cd tolerance are not fully understood. Ferrochelatase-1 (FC1, EC4.99.1.1) is the terminal enzyme of heme biosynthesis, catalyzing insertion of ferrous ion into protoporphyrin IX. Recent studies have shown that FC1 is involved in several physiological processes. However, its biological function associated with plant abiotic stress response is poorly understood.
resultsIn this study, we showed that AtFC1 was transcriptionally activated by Cd exposure. AtFC1 overexpression (35S::FC1) lines accumulated more Cd and non-protein thiol compounds than wild-type, and conferred plant tolerance to Cd stress, with improved primary root elongation, biomass and chlorophyll (Chl) content, and low degree of oxidation associated with reduced H
conclusionThese results indicate that AtFC1 would act as a positive regulator of plant tolerance to Cd stress. Our study will broaden our understanding of the role of FC1 in mediating plant response to Cd stress and provide a basis for further exploration of its downstream genes.
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