ArticleThe New phytologist2018
Comparative genomics reveals cotton-specific virulence factors in flexible genomic regions in Verticillium dahliae and evidence of horizontal gene transfer from Fusarium.
Article in The New phytologist, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
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50 citing papers in PubMed, 112 citations in OpenAlex.
- A structurally unique effector shared between vascular wilt fungi drives cotton and olive defoliation.Nature communications · 2026Article
- Verticillium Wilt of Cotton: Identification and Detection of the Causal Pathogen and Its Control.Plants (Basel, Switzerland) · 2026Review
- Starship giant transposons dominate plastic genomic regions in a fungal plant pathogen and drive virulence evolution.Nature communications · 2025Article
- Are Fungal Disease Outbreaks Instigated by Starship Transposons?Molecular plant pathology · 2025Review
- Verticillium dahliae Secretory Aspartyl Protease VdSAP Targets Cotton GhARP to Modulate Plant Defence and Defoliation.Molecular plant pathology · 2025Article
- CAP superfamily proteins (VdPRYs) manipulate plant immunity and contribute to the virulence ofMycology · 2025Article
- The acyl-CoA-binding protein VdAcb1 is essential for carbon starvation response and contributes to virulence inaBIOTECH · 2024Article
- Dual Transcriptome Analysis Reveals the Changes in Gene Expression in Both Cotton andJournal of fungi (Basel, Switzerland) · 2024Article
- The Kelch Repeat Protein VdKeR1 Is Essential for Development, Ergosterol Metabolism, and Virulence inJournal of fungi (Basel, Switzerland) · 2024Article
- Functional analysis of the mating type genes in Verticillium dahliae.BMC biology · 2024Article
- The Comparative Genomics of Botryosphaeriaceae Suggests Gene Families ofJournal of fungi (Basel, Switzerland) · 2024Article
- Article
- The elicitor VP2 from Verticillium dahliae triggers defence response in cotton.Plant biotechnology journal · 2024Article
- Genomic insights intoFrontiers in microbiology · 2024Review
- Two zinc finger proteins, VdZFP1 and VdZFP2, interact with VdCmr1 to promote melanized microsclerotia development and stress tolerance in Verticillium dahliae.BMC biology · 2023Article
- Genome-wide identification and analysis of a cotton secretome reveals its role in resistance against Verticillium dahliae.BMC biology · 2023Article
- TheInternational journal of molecular sciences · 2023Article
- Hypothetical Protein VDAG_07742 Is Required forInternational journal of molecular sciences · 2023Article
- Thioredoxin VdTrx1, an unconventional secreted protein, is a virulence factor inFrontiers in microbiology · 2023Article
- The secretome of Verticillium dahliae in collusion with plant defence responses modulates Verticillium wilt symptoms.Biological reviews of the Cambridge Philosophical Society · 2022Review
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Authors and funding
20 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Verticillium dahliae isolates are most virulent on the host from which they were originally isolated. Mechanisms underlying these dominant host adaptations are currently unknown. We sequenced the genome of V. dahliae Vd991, which is highly virulent on its original host, cotton, and performed comparisons with the reference genomes of JR2 (from tomato) and VdLs.17 (from lettuce). Pathogenicity-related factor prediction, orthology and multigene family classification, transcriptome analyses, phylogenetic analyses, and pathogenicity experiments were performed. The Vd991 genome harbored several exclusive, lineage-specific (LS) genes within LS regions (LSRs). Deletion mutants of the seven genes within one LSR (G-LSR2) in Vd991 were less virulent only on cotton. Integration of G-LSR2 genes individually into JR2 and VdLs.17 resulted in significantly enhanced virulence on cotton but did not affect virulence on tomato or lettuce. Transcription levels of the seven LS genes in Vd991 were higher during the early stages of cotton infection, as compared with other hosts. Phylogenetic analyses suggested that G-LSR2 was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer. Our results provide evidence that horizontal gene transfer from Fusarium to Vd991 contributed significantly to its adaptation to cotton and may represent a significant mechanism in the evolution of an asexual plant pathogen.
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