Evidence map›Paper›PMID 29084311›Full record

ArticleJAMA internal medicine2017

Work-Family Conflict and the Sex Difference in Depression Among Training Physicians.

Constance Guille, Elena Frank, Zhuo Zhao, David A Kalmbach, Paul J Nietert, Douglas A Mata, Srijan Sen

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in JAMA internal medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07087119 (A Pilot Study), which is not on this map. Cited by 88 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed, 3 pooled it
37.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07087119 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

A Pilot Study: Exploring The Role Of an Artificial Intelligence Powered Mental Health Support Tool For Mental Health Wellness For Physicians In Training

TypeinterventionalSponsorCedars-Sinai Medical CenterRan2025 to 2026Enrolled20ConditionsWellness, Psychological, Mental Health Wellness 1Armsutilization of artificial intelligence powered mental health support session through a web browser
3 · Its place in the literature

Who cites it

88 citing papers in PubMed, 3 syntheses or guidelines pooled it, 211 citations in OpenAlex.

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  10. Gender Differences in Self-Assessment Among Clerkship Medical Students Despite Equivalent Academic and Clinical Performance.Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry · 2026
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28 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Constance GuilleDepartment of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston.
Elena FrankDepartment of Psychiatry, University of Michigan, Ann Arbor.
Zhuo ZhaoDepartment of Psychiatry, University of Michigan, Ann Arbor.
David A KalmbachDepartment of Psychiatry, University of Michigan, Ann Arbor.
Paul J NietertDepartment of Public Health Sciences, Medical University of South Carolina, Charleston.
Douglas A MataProgram in Molecular Pathological Epidemiology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Srijan SenDepartment of Psychiatry, University of Michigan, Ann Arbor.
University of Michigan–Ann Arbor · USMedical University of South Carolina · USBrigham and Women's Hospital · US

Funding

South Carolina Clinical & Translational Research Institute (SCTR)UL1TR001450 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T., FLUME, PATRICK A · 2015 to 2024
$41.1M
Mobile Technology to Identify Behavorial Mechanisms Linking Genetic Variation and DepressionR01MH101459 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SEN, SRIJAN · 2013 to 2023
$6.4M
A Novel Approach to Reduce Pain, Prescription Opioid Use & Misuse in PregnancyK23DA039318 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI GUILLE, CONSTANCE · 2015 to 2017
$567k
NCATS NIH HHS UL1 TR001450NIDA NIH HHS K23 DA039318NIMH NIH HHS R01 MH101459
6 · The paper itself

Abstract

Importance: Depression is common among training physicians and may disproportionately affect women. The identification of modifiable risk factors is key to reducing this disease burden and its negative impact on patient care and physician career attrition. Objective: To determine the presence and magnitude of a sex difference in depressive symptoms and work-family conflict among training physicians; and if work-family conflict impacts the sex difference in depressive symptoms among training physicians. Design, Setting, and Participants: A prospective longitudinal cohort study of medical internship in the United States during the 2015 to 2016 academic year in which 3121 interns were recruited across all specialties from 44 medical institutions. Main Outcomes and Measures: Prior to and during their internship year, participants reported the degree to which work responsibilities interfered with family life using the Work Family Conflict Scale and depressive symptoms using the Patient Health Questionnaire-9 (PHQ-9). Results: Mean (SD) participant age was 27.5 (2.7) years, and 1571 participants (49.7%) were women. Both men and women experienced a marked increase in depressive symptoms during their internship year, with the increase being statistically significantly greater for women (men: mean increase in PHQ-9, 2.50; 95% CI, 2.26-2.73 vs women: mean increase, 3.20; 95% CI, 2.97-3.43). When work-family conflict was accounted for, the sex disparity in the increase in depressive symptoms decreased by 36%. Conclusions and Relevance: Our study demonstrates that depressive symptoms increase substantially during the internship year for men and women, but that this increase is greater for women. The study also identifies work-family conflict as an important potentially modifiable factor that is associated with elevated depressive symptoms in training physicians. Systemic modifications to alleviate conflict between work and family life may improve physician mental health and reduce the disproportionate depression disease burden for female physicians. Given that depression among physicians is associated with poor patient care and career attrition, efforts to alleviate depression among physicians has the potential to reduce the negative consequences associated with this disease.

Indexed as

Family ConflictInternship and ResidencyAdultDepressionFemaleHumansLongitudinal StudiesMalePhysiciansPhysicians, WomenProspective StudiesSex FactorsSurveys and QuestionnairesUnited States

Identifiers

PMID29084311
PMCPMC5820732
OpenAlexW2765221568

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.