ArticlePloS one2017
Effects of self-reported sensitivity and road-traffic noise levels on the immune system.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 57 citations in OpenAlex.
- Validation of road traffic noise and prediction of traffic increases along a highway in Hungary using noise maps.Environmental monitoring and assessment · 2026Article
- Beyond microbial exposure and colonization: multisensory shaping of the gut microbiome.mSystems · 2025Review
- A comprehensive review/expert statement on environmental risk factors of cardiovascular disease.Cardiovascular research · 2025Review
- Environmental noise perception and risk of poor mental health in a region on the Mediterranean coast of Spain.Environmental health and preventive medicine · 2025Article
- Transportation noise pollution as a cardiovascular risk factor: from epidemiological evidence to mechanistic insights.EXCLI journal · 2025Review
- Noise causes cardiovascular disease: it's time to act.Journal of exposure science & environmental epidemiology · 2025Review
- Effects of Environmental Noise Stress on Mouse Metabolism.International journal of molecular sciences · 2024Article
- Navigating the unknown: assessing anthropogenic threats to beaked whales, family Ziphiidae.Royal Society open science · 2024Article
- Crowdsourced cycling data applications to estimate noise pollution exposure during urban cycling.Heliyon · 2024Article
- Health position paper and redox perspectives - Disease burden by transportation noise.Redox biology · 2024Review
- Environmental risk factors and cardiovascular diseases: a comprehensive expert review.Cardiovascular research · 2022Article
- A Bayesian network model to predict the role of hospital noise, annoyance, and sensitivity in quality of patient care.BMC nursing · 2022Article
- Toxicopathological changes induced by combined exposure to noise and toluene in New Zealand White rabbits.Arhiv za higijenu rada i toksikologiju · 2022Article
- What Is the Role of Night-Time Noise Exposure in Childhood Allergic Disease?International journal of environmental research and public health · 2022Article
- Transportation noise pollution and cardiovascular disease.Nature reviews. Cardiology · 2021Review
- Environmental Conditions of Dance Rooms and Its Impact on Dance Conservatories Teachers' Health (An Andalusian Study).International journal of environmental research and public health · 2021Article
- Monitoring Sound and Its Perception during the Lockdown and De-Escalation of COVID-19 Pandemic: A Spanish Study.International journal of environmental research and public health · 2021Article
- Effects of noise and low-concentration carbon monoxide exposure on rat immunity.Journal of occupational health · 2021Article
- Oxidative stress and inflammation contribute to traffic noise-induced vascular and cerebral dysfunction via uncoupling of nitric oxide synthases.Redox biology · 2020Review
- The Immune System Can Hear Noise.Frontiers in immunology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sensitivity to noise, particularly road traffic noise, can increase cortisol levels and result in changes in immune system biomarkers. Therefore, continuous exposure to noise can have an effect on immune function, hormonal levels, and cardiovascular function, leading to hypertension and stress. The purpose of this study was to investigate the changes in stress-and immune system-related biomarkers according to the self-reported sensitivity to noise and exposure to road traffic noise, to ultimately determine the potential effects of noise on health. A survey was conducted through questionnaire (ISO/TS 15666) sent to 172 female subjects in Korea, including 128 from Ulsan and 44 from Seoul. The average noise level was calculated, and blood samples were collected for measurements of cortisol levels, Natural killer (NK) / Natural killer T (NKT) cell populations, and NK cell activity (through measurements of interleukin-12 (IL-12) and interferon-gamma (INF-γ) concentrations). Multivariate linear regression analysis of the measured biomarkers according to the road traffic noise level and self-reported noise sensitivity was conducted adjusting for the effects of age, alcohol status, smoking status, regular exercise, and residence period. IL-12 levels increased, whereas the NKT cell population decreased with increasing noise levels. The results further suggested that cortisol levels are more influenced by the subject's sensitivity to noise than to the level of chronic road traffic noise. Therefore, noise appears to have the largest effect on IL-12 levels as well as the population and activity of NKT cells. In conclusion, our results suggest that low-level road traffic noise and sensitivity to noise can affect health by causing changes in the immune response through mechanisms other than increased cortisol.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.