Evidence map›Paper›PMID 29084196›Full record

ReviewPediatric research2018

Multimodality neuromonitoring in severe pediatric traumatic brain injury.

Adam M H Young, Mathew R Guilfoyle, Joseph Donnelly, Peter Smielewski, Shruti Agarwal, Marek Czosnyka, Peter J Hutchinson

Open access · bronzeAbstract readReview
PubMed Publisher
In one paragraph

Review in Pediatric research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 32 citations in OpenAlex.

  1. Trial
  2. Cerebral autoregulation in pediatric and neonatal intensive care: A scoping review.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Monitoring cerebrovascular reactivity in pediatric traumatic brain injury: comparison of three methods.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021
    Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Adam M H YoungDepartment of Clinical Neurosciences, Division of Academic Neurosurgery, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.
Mathew R GuilfoyleDepartment of Clinical Neurosciences, Division of Academic Neurosurgery, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.
Joseph DonnellyDepartment of Clinical Neurosciences, Division of Academic Neurosurgery, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.
Peter SmielewskiDepartment of Clinical Neurosciences, Division of Academic Neurosurgery, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.
Shruti AgarwalDepartment of Pediatric intensive Care, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.
Marek CzosnykaDepartment of Clinical Neurosciences, Division of Academic Neurosurgery, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.
Peter J HutchinsonDepartment of Clinical Neurosciences, Division of Academic Neurosurgery, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.
University of Cambridge · GBAddenbrooke's Hospital · GB

Funding

Department of Health NIHR-RP-R3-12-013Medical Research Council G0600986Medical Research Council G1002277
6 · The paper itself

Abstract

Each year, the annual hospitalization rates of traumatic brain injury (TBI) in children in the United States are 57.7 per 100K in the <5 years of age and 23.1 per 100K in the 5-14 years age group. Despite this, little is known about the pathophysiology of TBI in children and how to manage it most effectively. Historically, TBI management has been guided by clinical examination. This has been assisted progressively by clinical imaging, intracranial pressure (ICP) monitoring, and finally a software that can calculate optimal brain physiology. Multimodality monitoring affords clinicians an early indication of secondary insults to the recovering brain including raised ICP and decreased cerebral perfusion pressure. From variables such as ICP and arterial blood pressure, correlations can be drawn to determine parameters of cerebral autoregulation (pressure reactivity index) and "optimal cerebral perfusion pressure" at which the vasculature is most reactive. More recently, significant advances using both direct and near-infrared spectroscopy-derived brain oxygenation plus cerebral microdialysis to drive management have been described. Here in, we provide a perspective on the state-of-the-art techniques recently implemented in clinical practice for pediatric TBI.

Indexed as

Multimodal ImagingBrainBrain Injuries, TraumaticCerebrovascular CirculationChildChild, PreschoolDiagnosis, Computer-AssistedHumansIntracranial PressureMagnetic Resonance ImagingMicrodialysisOxygenPerfusionPressureRiskSoftwareOxygen

Identifiers

PMID29084196
OpenAlexW2765448835

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.