ReviewMedical sciences (Basel, Switzerland)2016
Why Oats Are Safe and Healthy for Celiac Disease Patients.
Review in Medical sciences (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- European Society for the Study of Coeliac Disease (ESsCD) 2025 Updated Guidelines on the Diagnosis and Management of Coeliac Disease in Adults. Part 2: Management, Follow-Up, and Complex Disease Courses.United European gastroenterology journal · 2026Guideline
- Celiac Disease Management in School Environments: An Interdisciplinary Narrative Review of Operational, Psychosocial, and Nutritional Barriers.Nutrients · 2026Review
- Changes of Composition and Nutrition Value of Some Gluten Free (Pseudo)cereals by Addition of Carotenogenic Yeast Cell Homogenate.Molecules (Basel, Switzerland) · 2026Article
- Effects of Selected Cereal Concentrates and a Gluten-Free Diet on Ovarian, Testicular, and Thyroid Gland Morphology.Physiological research · 2026Article
- Management Strategy for Non-Responsive and Refractory Celiac Disease in Adults: A Review Article.Journal of clinical medicine · 2025Review
- To eat or not to eat oats: factors associated with oats consumption using the I-Change model.BMC public health · 2024Article
- Review
- Investigation of cost and availability of gluten-free food in Jeddah, KSA.Journal of Taibah University Medical Sciences · 2024Article
- Characteristics of Oat and Buckwheat Malt Grains for Use in the Production of Fermented Foods.Foods (Basel, Switzerland) · 2023Article
- Relationship between Oat Consumption, Gut Microbiota Modulation, and Short-Chain Fatty Acid Synthesis: An Integrative Review.Nutrients · 2023Review
- The Effect of Dietary Oat Consumption and Its Constituents on Fat Storage and Obesity.Physiological research · 2023Review
- Review
- Avenanthramides, Distinctive Hydroxycinnamoyl Conjugates of Oat,Plants (Basel, Switzerland) · 2023Review
- Does sourdough bread provide clinically relevant health benefits?Frontiers in nutrition · 2023Review
- Evaluating Germplasm of Cultivated Oat Species from the VIR Collection under the Russian Northwest Conditions.Plants (Basel, Switzerland) · 2022Article
- Analysis of oat seed transcriptome with regards to proteins involved in celiac disease.Scientific reports · 2022Article
- Quantification of Barley Contaminants in Gluten-Free Oats by Four Gluten ELISA Kits.Journal of agricultural and food chemistry · 2022Article
- Specific Avenin Cross-Reactivity with G12 Antibody in a Wide Range of Current Oat Cultivars.Foods (Basel, Switzerland) · 2022Article
- Effect of additional water supply during grain filling on protein composition and epitope characteristics of winter oats.Current research in food science · 2022Article
- Avenanthramides: Unique Bioactive Substances of Oat Grain in the Context of Cultivar, Cropping System, Weather Conditions and Other Grain Parameters.Plants (Basel, Switzerland) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The water-insoluble storage proteins of cereals (prolamins) are called "gluten" in wheat, barley, and rye, and "avenins" in oat. Gluten can provoke celiac disease (CD) in genetically susceptible individuals (those with human leukocyte antigen (HLA)-DQ2 or HLA-DQ8 serotypes). Avenins are present at a lower concentration (10%-15% of total protein content) in oat as compared to gluten in wheat (80%-85%). The avenins in the genus Avena (cultivated oat as well as various wild species of which gene bank accessions were analyzed) are free of the known CD immunogenic epitopes from wheat, barley, and rye. T cells that recognize avenin-specific epitopes have been found very rarely in CD patients. CD patients that consume oats daily do not show significantly increased levels of intraepithelial lymphocyte (EIL) cells. The safety and the positive health effects of the long-term inclusion of oats in the gluten-free diet have been confirmed in long-term studies. Since 2009 (EC 41/2009) and 2013 (FDA) oat products may be sold as gluten-free in several countries provided a gluten contamination level below 20 ppm. Introduction of oats in the gluten-free diet of celiac patients is advised after the recovery of the intestine. Health effects of oat consumption are reflected in European Food Safety Authority (EFSA)- and Food and Drug Administration (FDA)-approved health claims. Oats can form a healthy, nutritious, fiber-rich, and safe complement to the gluten-free diet.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.