Trial reportJournal of consulting and clinical psychology2017
Testing positive for a genetic predisposition to depression magnifies retrospective memory for depressive symptoms.
Trial report in Journal of consulting and clinical psychology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03998748 (Electrophysiological Correlates of Cognition in Depression), which is not on this map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Electrophysiological Correlates of Cognition in Depression
Who cites it
21 citing papers in PubMed.
- Limited impacts of biogenetic messaging on neural correlates of cognitive control and beliefs about depression.Cognitive, affective & behavioral neuroscience · 2023Trial
- Potential for Genomics to Help Guide Preventive Strategies in Psychiatry.JAMA psychiatry · 2026Article
- Effects of bogus genetic feedback on subjective and physiological responses to acute stress.Comprehensive psychoneuroendocrinology · 2026Article
- Polygenic scores in psychiatric research and clinical practice.Medizinische Genetik : Mitteilungsblatt des Berufsverbandes Medizinische Genetik e.V · 2026Article
- Viewing direct-to-consumer genetic test results for depression risk is psychologically well tolerated: Evidence from a longitudinal equivalence study.HGG advances · 2026Article
- Ethical and social issues in prediction of risk of severe mental illness: a scoping review and thematic analysis.BMC psychiatry · 2025Article
- Stratifying early-onset emotional disorders: using genetics to assess persistence in young people of European and South Asian ancestry.Journal of child psychology and psychiatry, and allied disciplines · 2024Article
- The undue influence of genetic information on senior medical students' treatment decisions.BMC medical education · 2023Article
- A qualitative study exploring the consumer experience of receiving self-initiated polygenic risk scores from a third-party website.European journal of human genetics : EJHG · 2023Article
- Genetic and Environmental Influences on Biological Essentialism, Heuristic Thinking, Need for Closure, and Conservative Values: Insights From a Survey and Twin Study.Behavior genetics · 2022Article
- The symptom discounting effect: what to do when negative genetic test results become risk factors for alcohol use disorder.Scientific reports · 2022Article
- Perceptions of best practices for return of results in an international survey of psychiatric genetics researchers.European journal of human genetics : EJHG · 2021Article
- Article
- Pygmalion in the Genes? On the potentially negative impacts of polygenic scores for educational attainment.Social psychology of education : an international journal · 2021Article
- Genetic feedback for psychiatric conditions: Where are we now and where are we going.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2020Review
- Article
- Impute.me: An Open-Source, Non-profit Tool for Using Data From Direct-to-Consumer Genetic Testing to Calculate and Interpret Polygenic Risk Scores.Frontiers in genetics · 2020Article
- Biomedical Explanations of Psychopathology and Their Implications for Attitudes and Beliefs About Mental Disorders.Annual review of clinical psychology · 2019Review
- The Implications of Genetic and Other Biological Explanations for Thinking about Mental Disorders.The Hastings Center report · 2019Review
- Self-rated amygdala activity: an auto-biological index of affective distress.Personality neuroscience · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
objectiveDepression, like other mental disorders and health conditions generally, is increasingly construed as genetically based. This research sought to determine whether merely telling people that they have a genetic predisposition to depression can cause them to retroactively remember having experienced it.
methodU.S. adults (men and women) were recruited online to participate (Experiment 1: N = 288; Experiment 2: N = 599). After conducting a test disguised as genetic screening, we randomly assigned some participants to be told that they carried elevated genetic susceptibility to depression, whereas others were told that they did not carry this genetic liability or were told that they carried elevated susceptibility to a different disorder. Participants then rated their experience of depressive symptoms over the prior 2 weeks on a modified version of the Beck Depression Inventory-II.
resultsParticipants who were told that their genes predisposed them to depression generally reported higher levels of depressive symptomatology over the previous 2 weeks, compared to those who did not receive this feedback.
conclusionsGiven the central role of self-report in psychiatric diagnosis, these findings highlight potentially harmful consequences of personalized genetic testing in mental health. (PsycINFO Database Record
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.