Evidence map›Paper›PMID 29083166›Full record

ArticleJournal of the American Chemical Society2017

Enantiomeric Recognition of d- and l-Lactate by CEST with the Aid of a Paramagnetic Shift Reagent.

Lei Zhang, André F Martins, Piyu Zhao, Michael Tieu, David Esteban-Gómez, Gregory T McCandless, Carlos Platas-Iglesias, A Dean Sherry

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Journal of pharmaceutical analysis · 2026
    Article
  3. Article
  4. Article
  5. StereoPHIP: Stereoselective Parahydrogen-Induced Polarization.Angewandte Chemie (International ed. in English) · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lei ZhangDepartment of Chemistry, University of Texas at Dallas , 800 West Campbell Road, Richardson, Texas 75080, United States.
André F MartinsDepartment of Chemistry, University of Texas at Dallas , 800 West Campbell Road, Richardson, Texas 75080, United States.
Piyu ZhaoDepartment of Chemistry, University of Texas at Dallas , 800 West Campbell Road, Richardson, Texas 75080, United States.
Michael TieuDepartment of Chemistry, University of Texas at Dallas , 800 West Campbell Road, Richardson, Texas 75080, United States.
David Esteban-GómezDepartamento de Química, Facultade de Ciencias & Centro de Investigacións Científicas Avanzadas (CICA), Universidade da Coruña , 15071 A Coruña, Spain.
Gregory T McCandlessDepartment of Chemistry, University of Texas at Dallas , 800 West Campbell Road, Richardson, Texas 75080, United States.
Carlos Platas-IglesiasDepartamento de Química, Facultade de Ciencias & Centro de Investigacións Científicas Avanzadas (CICA), Universidade da Coruña , 15071 A Coruña, Spain.
A Dean SherryDepartment of Chemistry, University of Texas at Dallas , 800 West Campbell Road, Richardson, Texas 75080, United States.ORCID 0000-0001-7150-8301

Funding

UT Southwestern Medical Center Simmons Comprehensive Cancer CenterP30CA142543 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI MELANIE H. COBB · 2010 to 2026
$53.7M
TR&D 3: Imaging Carbohydrate MetabolismP41EB015908 · NIBIB · UT SOUTHWESTERN MEDICAL CENTER · PI MALLOY, CRAIG R · 2012 to 2021
$10.9M
PARACEST AGENTS FOR MOLECULAR IMAGING OF CANCER BY MRIR01CA115531 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI SHERRY, DEAN · 2005 to 2021
$4.2M
Evaluation of Iodorotenone, A SPECT Perfusion TracerR01EB000482 · NIBIB · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI VANBROCKLIN, HENRY F. · 2003 to 2005
$1.5M
NCI NIH HHS P30 CA142543NCI NIH HHS R01 CA115531NIBIB NIH HHS P41 EB015908NIBIB NIH HHS R01 EB000482
6 · The paper itself

Abstract

A previous report demonstrated that EuDO3A could be used as an NMR shift reagent for imaging extracellular lactate produced by cancer cells using CEST imaging. In this work, a series of heptadentate macrocyclic YbDO3A-trisamide complexes with δ-chiral carbons in the three pendant side-arms were examined as shift reagents for lactate detection. High resolution

Indexed as

Indicators and ReagentsLactic AcidLanthanoid Series ElementsMagnetic Resonance SpectroscopyIndicators and ReagentsLactic AcidLanthanoid Series Elements

Identifiers

PMID29083166
PMCPMC5796655

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.