Evidence map›Paper›PMID 29083162›Full record

ArticleAnalytical chemistry2017

Evaluating Metabolite-Related DNA Oxidation and Adduct Damage from Aryl Amines Using a Microfluidic ECL Array.

Itti Bist, Snehasis Bhakta, Di Jiang, Tia E Keyes, Aaron Martin, Robert J Forster, James F Rusling

Abstract read
In one paragraph

Article in Analytical chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Itti Bist
Snehasis Bhakta
Di Jiang
Tia E KeyesSchool of Chemical Sciences, Dublin City University , Dublin 9, Ireland.ORCID 0000-0002-4604-5533
Aaron MartinSchool of Chemical Sciences, Dublin City University , Dublin 9, Ireland.
Robert J ForsterSchool of Chemical Sciences, Dublin City University , Dublin 9, Ireland.ORCID 0000-0001-5079-3123
James F RuslingDepartment of Surgery and Neag Cancer Center, UConn Health , Farmington, Connecticut 06032, United States.ORCID 0000-0002-6117-3306
Dublin City University · IEOllscoil na Gaillimhe – University of Galway · IE

Funding

ELECTROCATALYTIC STUDIES OF TOXIC POLLUTANT ACTIVATIONR01ES003154 · NIEHS · UNIVERSITY OF CONNECTICUT STORRS · PI RUSLING, JAMES F. · 1985 to 2018
$6.1M
NIEHS NIH HHS R01 ES003154
6 · The paper itself

Abstract

Damage to DNA from the metabolites of drugs and pollutants constitutes a major human toxicity pathway known as genotoxicity. Metabolites can react with metal ions and NADPH to oxidize DNA or participate in S

Indexed as

Electrochemical TechniquesLuminescent MeasurementsMicrofluidic Analytical TechniquesAminesCopperCytochrome P-450 Enzyme SystemDNADNA AdductsDNA DamageHumansNADPOxidation-ReductionAminesCopperCytochrome P-450 Enzyme SystemDNADNA AdductsNADP

Identifiers

PMID29083162
PMCPMC5777145
OpenAlexW2766238668

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.