Evidence map›Paper›PMID 29082754›Full record

ArticleAnnals of human biology2017

Longitudinal changes in BMI z-scores among 45 414 2-4-year olds with severe obesity.

David S Freedman, Nancy F Butte, Elsie M Taveras, Alyson B Goodman, Heidi M Blanck

Registry-linked trialAbstract read
In one paragraph

Article in Annals of human biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05041855 (Family Inclusive Childhood Obesity Treatment Designed for Low Income and Hispanic Families), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05041855 naactive not recruitingnot on this mapstarted 2021, after this paper: background citation

Family Inclusive Childhood Obesity Treatment Designed for Low Income and Hispanic Families

TypeinterventionalSponsorUniversity of Colorado, DenverRan2021 to 2026Enrolled554ConditionsPediatric Obesity, Healthy Eating, Physical Activity, Minority HealthArmsThe Healthy Living Program/La Vida Saludable, Recommended Treatment of Obesity in Primary Care
3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

David S Freedmana Division of Nutrition, Physical Activity and Obesity , Centers for Disease Control and Prevention , Atlanta , GA , USA.
Nancy F Butteb Baylor College of Medicine , Children's Nutrition Research Center , Houston , TX , USA.
Elsie M Taverasc Department of Pediatrics , MassGeneral Hospital for Children , Boston , MA , USA.
Alyson B Goodmana Division of Nutrition, Physical Activity and Obesity , Centers for Disease Control and Prevention , Atlanta , GA , USA.
Heidi M Blancka Division of Nutrition, Physical Activity and Obesity , Centers for Disease Control and Prevention , Atlanta , GA , USA.

Funding

GENETICS OF CHILDHOOD OBESITYR01DK059264 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI BUTTE, NANCY F · 2000 to 2004
$2.7M
Patient Oriented Research and Mentorship in Childhood Obesity DisparitiesK24DK105989 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI TAVERAS BENAVIDEZ, ELSIE MIREYA · 2015 to 2019
$907k
Intramural CDC HHS CC999999NCCDPHP CDC HHS U18 DP003370NIDDK NIH HHS K24 DK105989NIDDK NIH HHS R01 DK059264
6 · The paper itself

Abstract

backgroundBMI z-scores (BMIz) based on the Centers for Disease Control and Prevention (CDC) growth charts among children do not accurately characterise BMI levels among children with very high BMIs. These limitations may be particularly relevant in longitudinal and intervention studies, as the large changes in the L (normality) and S (dispersion) parameters with age can influence BMIz.

aimTo compare longitudinal changes in BMIz with BMI expressed as a percentage of the 95th percentile (%BMIp95) and a modified z-score calculated as log(BMI/M)/S. SUBJECTS AND

methodsA total of 45 414 2-4-year-olds with severe obesity (%BMIp95 ≥ 120).

resultsChanges in very high BMIz levels differed from the other metrics. Among severely obese 2-year-old girls, for example, the mean BMIz decreased by 0.6 SD between examinations, but there were only small changes in BMIp95 and modified BMIz. Some 2-year-old girls had BMIz decreases of >1 SD, even though they had large increases in BMI, %BMIp95 and modified BMIz.

conclusionsAmong children with severe obesity, BMIz changes may be due to differences in the transformations used to estimate levels of BMIz rather than to changes in body size. The BMIs of these children could be expressed relative to the 95th percentile or as modified z-scores.

Indexed as

Body Mass IndexChild, PreschoolFemaleHumansLongitudinal StudiesMaleObesity, MorbidBMIchildrenLMSlongitudinal

Identifiers

PMID29082754
PMCPMC5765752

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.