Evidence map›Paper›PMID 29082671›Full record

ArticlePediatric pulmonology2017

Pulmonary function disparities exist and persist in Hispanic patients with cystic fibrosis: A longitudinal analysis.

Meghan E McGarry, John M Neuhaus, Dennis W Nielson, Esteban Burchard, Ngoc P Ly

Open access · greenAbstract read
In one paragraph

Article in Pediatric pulmonology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Article
  4. Review
  5. Article
  6. Racial inequities and rareJournal of clinical & translational endocrinology · 2024
    Article
  7. Article
  8. Article
  9. Observational
  10. Review
  11. Ethnic differences in staphylococcus aureus acquisition in cystic fibrosis.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2023
    Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Disease burden in people with cystic fibrosis heterozygous for F508del and a minimal function mutation.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2022
    Observational
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Meghan E McGarryDepartment of Pediatrics, University of California, San Francisco, California.ORCID http://orcid.org/0000-0002-8562-7018
John M NeuhausDepartment of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California.
Dennis W NielsonDepartment of Pediatrics, University of California, San Francisco, California.
Esteban BurchardDepartment of Bioengineering and Therapeutic Sciences, University of California, San Francisco, California.
Ngoc P LyDepartment of Pediatrics, University of California, San Francisco, California.
University of California, San Francisco · US

Funding

SynthesisP30DK072517 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI VERKMAN, ALAN S · 2005 to 2022
$18.1M
The Airway Functional Genomics of Bronchodilator Drug Response in Minority Children with AsthmaR01HL117004 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AHITUV, NADAV, SEIBOLD, MAX A · 2013 to 2022
$9.3M
CLINICAL, PHARMACOLOGY, DRUG ACTION &PHARMACOKINETICST32GM007546 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Radojka Savic · 1985 to 2026
$8.9M
Social Interventions to address disparities In young adult tobacco useP60MD006902 · NIMHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BIBBINS-DOMINGO, KIRSTEN · 2012 to 2016
$6.4M
Gene-environments and Admixture in Latino Asthmatics (GALA 2)R01ES015794 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BURCHARD, ESTEBAN GONZALEZ · 2008 to 2012
$5.4M
Clinical and Molecular Phenotypes of Severe AsthmaU10HL109146 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FAHY, JOHN V · 2011 to 2016
$4.0M
Genes, air pollution, and asthma severity in minority childrenR01MD010443 · NIMHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SEIBOLD, MAX A, ZIV, ELAD · 2016 to 2020
$3.8M
Genetic Control of Airway Epithelium Gene Expression in Childhood AsthmaticsR01HL128439 · NHLBI · NATIONAL JEWISH HEALTH · PI SEIBOLD, MAX A · 2015 to 2019
$3.1M
Risk Factors For Worse Lung Function In Latinos With Cystic FibrosisK23HL133437 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MCGARRY, MEGHAN ELIZABETH · 2018 to 2023
$1.0M
Gene-Environment Analyses of Early Life Exposures and Asthma in Ethnically Diverse ChildrenR21ES024844 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BURCHARD, ESTEBAN GONZALEZ, GAUDERMAN, WILLIAM JAMES · 2015 to 2017
$509k
NHLBI NIH HHS K23 HL133437NHLBI NIH HHS R01 HL117004NHLBI NIH HHS R01 HL128439NHLBI NIH HHS U10 HL109146NIDDK NIH HHS P30 DK072517NIEHS NIH HHS R01 ES015794NIEHS NIH HHS R21 ES024844NIGMS NIH HHS T32 GM007546NIMHD NIH HHS L60 MD010865NIMHD NIH HHS P60 MD006902NIMHD NIH HHS R01 MD010443
6 · The paper itself

Abstract

backgroundHispanic patients with cystic fibrosis (CF) have decreased life expectancy compared to non-Hispanic white patients. Pulmonary function is a main predictor of life expectancy in CF. Ethnic differences in pulmonary function in CF have been understudied. The objective was to compare longitudinal pulmonary function between Hispanic and non-Hispanic white patients with CF.

methodsThis cohort study of 15 018 6-25 years old patients in the CF Foundation Patient Registry from 2008 to 2013 compared FEV

resultsHispanic patients had lower FEV

conclusionsDisparities in pulmonary function exist in Hispanic patients with CF early in life and then persist without improving or worsening over time. It is valuable to investigate the factors contributing to pulmonary function in Hispanic patients with CF.

Indexed as

AdolescentAdultChildCohort StudiesCystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorFemaleForced Expiratory VolumeHeterozygoteHispanic or LatinoHomozygoteHumansLungMaleYoung AdultCystic Fibrosis Transmembrane Conductance Regulatorcystic fibrosis (CF)epidemiologyhealthcare disparitieshispanic latinopulmonary function testing (PFT)social dimensions of pulmonary medicine

Identifiers

PMID29082671
PMCPMC5693693
OpenAlexW2767145415

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.