Evidence map›Paper›PMID 29082439›Full record

ReviewJournal of neural transmission (Vienna, Austria : 1996)2019

The role of depression pharmacogenetic decision support tools in shared decision making.

Katarina Arandjelovic, Harris A Eyre, Eric Lenze, Ajeet B Singh, Michael Berk, Chad Bousman

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of neural transmission (Vienna, Austria : 1996), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Pharmacogenetic Testing Knowledge and Attitudes among Pediatric Psychiatrists and Pediatricians in Alberta, Canada.Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent · 2022
    Article
  5. Encountering Pharmacogenetic Test Results in the Psychiatric Clinic.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2022
    Article
  6. Article
  7. Treatment-Resistant Depression Revisited: A Glimmer of Hope.Journal of personalized medicine · 2021
    Review
  8. Review
  9. Review
  10. Challenges and Future Prospects of Precision Medicine in Psychiatry.Pharmacogenomics and personalized medicine · 2020
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Katarina ArandjelovicIMPACT SRC, School of Medicine, Deakin University, Geelong, VIC, 3216, Australia. k.arandjelovic@icloud.com.ORCID 0000-0003-0926-5657
Harris A EyreIMPACT SRC, School of Medicine, Deakin University, Geelong, VIC, 3216, Australia.
Eric LenzeDepartment of Psychiatry, Washington University School of Medicine, St Louis, MO, USA.
Ajeet B SinghIMPACT SRC, School of Medicine, Deakin University, Geelong, VIC, 3216, Australia.
Michael BerkIMPACT SRC, School of Medicine, Deakin University, Geelong, VIC, 3216, Australia.
Chad BousmanDepartment of Psychiatry, University of Melbourne, Melbourne, VIC, Australia.

Funding

National Health and Medical Research Council 1059660
6 · The paper itself

Abstract

Patients discontinue antidepressant medications due to lack of knowledge, unrealistic expectations, and/or unacceptable side effects. Shared decision making (SDM) invites patients to play an active role in their treatment and may indirectly improve outcomes through enhanced engagement in care, adherence to treatment, and positive expectancy of medication outcomes. We believe decisional aids, such as pharmacogenetic decision support tools (PDSTs), facilitate SDM in the clinical setting. PDSTs may likewise predict drug tolerance and efficacy, and therefore adherence and effectiveness on an individual-patient level. There are several important ethical considerations to be navigated when integrating PDSTs into clinical practice. The field requires greater empirical research to demonstrate clinical utility, and the mechanisms thereof, as well as exploration of the ethical use of these technologies.

Indexed as

Decision Making, SharedDecision Support TechniquesPatient ParticipationPharmacogeneticsAntidepressive AgentsDepressive DisorderHumansAntidepressive AgentsAdherenceAntidepressantsDecision support toolPharmacogeneticsPsychoeducationShared decision makingTherapeutic alliance

Identifiers

PMID29082439

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.