Evidence map›Paper›PMID 29082358›Full record

ArticleJBMR plus2017

Conditional Disruption of

Kin-Hing William Lau, Virginia M Stiffel, Charles H Rundle, Mehran Amoui, Jordan Tapia, Tyler D White, Matilda H-C Sheng

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JBMR plus, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kin-Hing William LauMusculoskeletal Disease Center, Jerry L. Pettis Memorial V.A. Medical Center, Loma Linda, California 92357, U.S.A.
Virginia M StiffelMusculoskeletal Disease Center, Jerry L. Pettis Memorial V.A. Medical Center, Loma Linda, California 92357, U.S.A.
Charles H RundleMusculoskeletal Disease Center, Jerry L. Pettis Memorial V.A. Medical Center, Loma Linda, California 92357, U.S.A.
Mehran AmouiMusculoskeletal Disease Center, Jerry L. Pettis Memorial V.A. Medical Center, Loma Linda, California 92357, U.S.A.
Jordan TapiaMusculoskeletal Disease Center, Jerry L. Pettis Memorial V.A. Medical Center, Loma Linda, California 92357, U.S.A.
Tyler D WhiteMusculoskeletal Disease Center, Jerry L. Pettis Memorial V.A. Medical Center, Loma Linda, California 92357, U.S.A.
Matilda H-C ShengDepartment of Medicine, Loma Linda University School of Medicine, Loma Linda, California 92350, U.S.A.
Jerry L. Pettis Memorial VA Medical Center · USLoma Linda University · US

Funding

Regulation of Functional Activity of OsteoclastsI01BX002964 · VA · VA LOMA LINDA HEALTHCARE SYSTEM · PI LAU, KIN-HING WILLIAM · 2016 to 2019
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BLR&D Research Career Scientist AwardIK6BX003782 · VA · VA LOMA LINDA HEALTHCARE SYSTEM · PI LAU, KIN-HING WILLIAM · 2017 to 2021
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BLRD VA I01 BX002964BLRD VA IK6 BX003782
6 · The paper itself

Abstract

This study sought to understand the regulation of an osteoclastic protein-tyrosine phosphatase (PTP-oc), a positive regulator of osteoclast activaty. Our past studies suggested that PTP-oc is regulated post-transcriptionally. The 3'-UTR of PTP-oc mRNA contains a target site for

Indexed as

Cell/Tissue signalingepigeneticsgenetic animal modelsmolecular pathways – remodelingOsteoclasts

Identifiers

PMID29082358
PMCPMC5656011
OpenAlexW2740782335

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.