ArticleInternational journal of nursing sciences2016
Effectiveness of LISTEN on loneliness, neuroimmunological stress response, psychosocial functioning, quality of life, and physical health measures of chronic illness.
Article in International journal of nursing sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 7 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Pooled it
- What works to reduce loneliness: a rapid systematic review of 101 interventions.Journal of public health policy · 2025Pooled it
- Interventions to Reduce Loneliness in Community-Living Older Adults: a Systematic Review and Meta-analysis.Journal of general internal medicine · 2024Pooled it
- Can we mitigate the psychological impacts of social isolation using behavioural activation? Long-term results of the UK BASIL urgent public health COVID-19 pilot randomised controlled trial and living systematic review.Evidence-based mental health · 2022Pooled it
- Interventions Associated With Reduced Loneliness and Social Isolation in Older Adults: A Systematic Review and Meta-analysis.JAMA network open · 2022Pooled it
- Interventions to improve social connections: a systematic review and meta-analysis.Social psychiatry and psychiatric epidemiology · 2022Pooled it
- Psychosocial Interventions and Immune System Function: A Systematic Review and Meta-analysis of Randomized Clinical Trials.JAMA psychiatry · 2020Pooled it
- Loneliness and cognitive aging: a brain-heart axis perspective on a modifiable risk.Frontiers in aging · 2026Review
- Nurse-led pathways for loneliness and social isolation in older adults: a narrative review of assessment, relational mechanisms, and implementation.Frontiers in public health · 2026Review
- Evaluating Intensity, Complexity, and Potential for Causal Inference in Social Needs Interventions: A Review of a Scoping Review.JAMA network open · 2024Article
- Assessing Loneliness among Adults Receiving Outpatient Treatment with Medication for Opioid Use Disorder (MOUD).International journal of environmental research and public health · 2022Article
- Loneliness: An Immunometabolic Syndrome.International journal of environmental research and public health · 2021Review
- Altered immunoemotional regulatory system in COVID-19: From the origins to opportunities.Journal of neuroimmunology · 2021Review
- An observational study protocol to explore loneliness and systemic inflammation in an older adult population with chronic venous leg ulcers.BMC geriatrics · 2021Article
- Psychological maladjustment mediates the link between remembrances of parental rejection in childhood and loneliness in adulthood: A cross-cultural comparative study.International journal of psychology : Journal international de psychologie · 2020Article
- Lonesome no more? A two-year follow-up of internet-administered cognitive behavioral therapy for loneliness.Internet interventions · 2020Article
- Loneliness in middle age and biomarkers of systemic inflammation: Findings from Midlife in the United States.Social science & medicine (1982) · 2018Article
- The effectiveness of mI SMART: A nurse practitioner led technology intervention for multiple chronic conditions in primary care.International journal of nursing sciences · 2018Article
- Life after stroke in Appalachia.International journal of nursing sciences · 2017Article
- A Pilot One Group Feasibility, Acceptability, and Initial Efficacy Trial of LISTEN for Loneliness in Lonely Stroke Survivors.SAGE open nursingArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
objectivesLoneliness is a biopsychosocial determinant of health and contributes to physical and psychological chronic illnesses, functional decline, and mortality in older adults. This paper presents the results of the first randomized trial of LISTEN, which is a new cognitive behavioral intervention for loneliness, on loneliness, neuroimmunological stress response, psychosocial functioning, quality of life, and measures of physical health.
methodsThe effectiveness of LISTEN was evaluated in a sample population comprising 27 lonely, chronically ill, older adults living in Appalachia. Participants were randomized into LISTEN or educational attention control groups. Outcome measures included salivary cortisol and DHEA, interleukin-6, interleukin-2, depressive symptoms, loneliness, perceived social support, functional ability, quality of life, fasting glucose, blood pressure, and body mass index.
resultsAt 12 weeks after the last intervention session, participants of the LISTEN group reported reduced loneliness (
conclusionsLISTEN can effectively diminish loneliness and decrease the systolic blood pressure in community-dwelling, chronically ill, older adults. Results indicate that this population, if left with untreated loneliness, may experience functional impairment over a period as short as 4 months. Further studies on LISTEN are needed with larger samples, in varied populations, and over longer periods of time to assess the long-term effects of diminishing loneliness in multiple chronic conditions.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.