Evidence map›Paper›PMID 29082260›Full record

ArticleJournal of diabetes research2017

Fulminant Type 1 Diabetes in Children: A Multicenter Study in China.

Yi Gu, Yi Wang, Pin Li, Haiyan Wei, Linqi Chen, Qianqi Liu, Yu Liu, Qiaozhi Yang, Xinran Cheng, Lanjie He and 9 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of diabetes research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. A Japanese infant with fulminant type 1 diabetes with disease-sensitiveClinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology · 2025
    Article
  2. Review
  3. [Clinical Analysis of 17 Adult Patients With Fulminant Type 1 Diabetes Mellitus].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2023
    Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Yi GuNational Key Discipline of Pediatrics, Department of Endocrinology, Genetics and Metabolism, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China.
Yi WangNational Key Discipline of Pediatrics, Department of Endocrinology, Genetics and Metabolism, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China.
Pin LiDepartment of Endocrinology, Children's Hospital of Shanghai, Shanghai Jiao Tong University, Shanghai 200062, China.
Haiyan WeiDepartment of Endocrinology and Genetic Metabolism, Zhengzhou Children's Hospital, Zhengzhou 450053, China.
Linqi ChenDepartment of Endocrinology, Children's Hospital of Soochow University, Suzhou 215003, China.
Qianqi LiuDepartment of Endocrinology, Nanjing Children's Hospital of Nanjing Medical University, Nanjing 210005, China.ORCID 0000-0003-0405-4682
Yu LiuDepartment of Endocrinology, Genetics and Metabolism, The Children's Hospital of Guiyang City, Guiyang 550003, China.
Qiaozhi YangDepartment of Pediatric, Liaocheng Children's Hospital, Shandong 252002, China.
Xinran ChengThe Pediatric Endocrine Department, Chengdu Woman and Children's Center Hospital, Chengdu 610091, China.
Lanjie HeDepartment of Pediatric, General Hospital of Ningxia Medical University, Yinchuan 750004, China.
Liya WeiNational Key Discipline of Pediatrics, Department of Endocrinology, Genetics and Metabolism, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China.ORCID 0000-0001-5716-4178
Zhiying ZhuDepartment of Endocrinology, Children's Hospital of Shanghai, Shanghai Jiao Tong University, Shanghai 200062, China.
Yongxing ChenDepartment of Endocrinology and Genetic Metabolism, Zhengzhou Children's Hospital, Zhengzhou 450053, China.
Fengyun WangDepartment of Endocrinology, Children's Hospital of Soochow University, Suzhou 215003, China.
Xing ShiDepartment of Endocrinology, Nanjing Children's Hospital of Nanjing Medical University, Nanjing 210005, China.
Yuxian ChengDepartment of Pediatric, Liaocheng Children's Hospital, Shandong 252002, China.
Yan WeiThe Pediatric Endocrine Department, Chengdu Woman and Children's Center Hospital, Chengdu 610091, China.
Jianing YuDepartment of Pediatric, General Hospital of Ningxia Medical University, Yinchuan 750004, China.
Chunxiu GongNational Key Discipline of Pediatrics, Department of Endocrinology, Genetics and Metabolism, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China.ORCID 0000-0002-1262-7383

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo investigate the hospital-based incidence of FT1D in Chinese children and compare the clinical feature with classical T1DM.

methodsA cross-sectional study with sixteen hospitals involved. We obtained 23 FT1D cases as group 1, acute-onset T1DM as group 2, and typical T1DM as group 3.

resultsThe incidence of FT1D was 1.56% in 16 participating hospitals. The mean age at the onset of group 1 was 2.00 (1.08, 6.51) years old, much younger than that of group 2 (6.11 (3.92, 9.50)) and group 3 (6.92 (4.17, 10.03)). In addition, significant differences were found between three groups: mean BMI and flu-like symptoms with fever and abdominal pain. Follow-up comparison of three groups from Beijing Children's Hospital for at least one year showed that there is no significant difference between the three groups in terms of mean HbA1c levels and insulin injection dosages.

conclusionFT1D onset age is much younger than that of classical T1D patients. The hospital-based incidence of FT1D in Chinese children was 1.56% in all new-onset T1DM. For the diagnosis, making FT1D alone into a subtype within type 1 diabetes may be meaningful. However, for the treatment and prognosis, such classification should not be helpful to the clinic.

Indexed as

Age of OnsetBiomarkersBlood GlucoseChildChild, PreschoolChinaCross-Sectional StudiesDiabetes Mellitus, Type 1FemaleGlycated HemoglobinHospitalsHumansHypoglycemic AgentsIncidenceInfantInsulinBiomarkersBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humanHypoglycemic AgentsInsulin

Identifiers

PMID29082260
PMCPMC5634598

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.