Evidence map›Paper›PMID 29082259›Full record

ArticleJournal of diabetes research2017

Effects of Renal Denervation on Insulin Sensitivity and Inflammatory Markers in Nondiabetic Patients with Treatment-Resistant Hypertension.

Ulla Kampmann, Ole N Mathiassen, Kent L Christensen, Niels H Buus, Mette Bjerre, Henrik Vase, Niels Møller, Anne Kaltoft, Per L Poulsen

Open access · goldAbstract read
In one paragraph

Article in Journal of diabetes research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Renal denervation for resistant hypertension.The Cochrane database of systematic reviews · 2021
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Inflammatory Biomarkers in Hypertension.Current medicinal chemistry · 2025
    Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Renal Inflammation in DOCA-Salt Hypertension.Hypertension (Dallas, Tex. : 1979) · 2019
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ulla KampmannDepartment of Endocrinology and Internal Medicine, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus C, Denmark.ORCID 0000-0002-2234-7780
Ole N MathiassenDepartment of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus, Denmark.
Kent L ChristensenDepartment of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus, Denmark.
Niels H BuusDepartment of Nephrology, Aalborg University Hospital, Hobrovej 18-22, 9000 Aalborg, Denmark.
Mette BjerreMedical Research Laboratory, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus C, Denmark.
Henrik VaseDepartment of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus, Denmark.
Niels MøllerDepartment of Endocrinology and Internal Medicine, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus C, Denmark.
Anne KaltoftDepartment of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus, Denmark.
Per L PoulsenDepartment of Endocrinology and Internal Medicine, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus C, Denmark.
Aarhus University Hospital · DKAalborg University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increased sympathetic activity is important in the pathogenesis of hypertension and insulin resistance. Afferent signaling from the kidneys elevates the central sympathetic drive. We investigated the effect of catheter-based renal sympathetic denervation (RDN) on glucose metabolism, inflammatory markers, and blood pressure in nondiabetic patients with treatment-resistant hypertension. Eight subjects were included in an open-labelled study. Each patient was studied before and 6 months after RDN. Endogenous glucose production was assessed by a 3-

Indexed as

Blood PressureCatheter AblationInsulin ResistanceAdultAgedAntihypertensive AgentsBiomarkersBlood GlucoseDrug ResistanceFemaleGlycated HemoglobinHumansHypertensionInflammation MediatorsInsulinKidneyAntihypertensive AgentsBiomarkersBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humanInflammation MediatorsInsulin

Identifiers

PMID29082259
PMCPMC5610868
OpenAlexW2752435219

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.